Strongest Disposable Vapes for 420: 8 Must-Try Vapes
420 is the day to go big or go home. If you want to take your sesh to new heights, not just any vape will do. Weak hits? Not today. You need something with some serious kick that’ll have you floating before you even realize what happened.
That’s where high-potency disposable vapes come in. The strongest ones are packing THCh and THCp, two of the most powerful cannabinoids on the market. These aren’t your average disposables. These kinds hit like a freight train and keep the good vibes rolling.
This guide covers the absolute strongest disposable vapes for 420, so you can skip the weak stuff and go straight for the heavy hitters. Let’s get into it because today is all about elevating your celebration.
Key Takeaways
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High-potency disposable vapes are perfect for an unforgettable 420 experience.
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THCp is the strongest known cannabinoid, binding to CB1 receptors 33 times more effectively than Delta 9 THC.
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THCh is another ultra-potent cannabinoid, offering a powerful yet smoother high.
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Mellow Fellow’s disposables are lab-tested, ensuring safety and potency.
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Strain selection affects the experience, with indicas for relaxation, sativas for energy, and hybrids for balance.
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Starting April 1st, Mellow Fellow will offer three weeks of savings for these disposables, and much more!
Why High-Potency Vapes Are Perfect for 420 Celebrations
420 is the one day of the year when going all out is practically a requirement. Whether you're kicking back with friends or settling in for a solo session, the goal is the same: achieving the kind of high that makes the day unforgettable. That’s where high-potency disposable vapes come in.
These vapes offer a fast-acting, hard-hitting experience, perfect for seasoned users who want something stronger than standard THC products. Since they’re discreet, portable, and ready to use straight out of the box, they’re ideal for social gatherings, group smoke sessions, or just keeping things simple while still getting sky-high.
But not all disposables are created equal. The strongest options on the market contain powerful cannabinoids like THCp and THCh, which can take your 420 experience to the next level.
Understanding Cannabinoid Potency
Not all THC is the same, and if you’re chasing the strongest effects, it helps to know what makes some cannabinoids hit harder than others.
THCp: The Strongest Known Cannabinoid
THCp (tetrahydrocannabiphorol) is considered the most potent naturally occurring cannabinoid currently available. Research suggests that THCp binds to CB1 receptors up to 33 times more effectively than Delta 9 THC, meaning even small amounts can produce extremely strong effects.
What to expect from a THCp high:
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A rapid onset of euphoria and deep relaxation
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Intense body and cerebral effects, often lasting longer than Delta 9
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A much heavier, more immersive high which is great for experienced users
THCh: A Close Second in Strength
THCh (tetrahydrocannabihexol) is another powerhouse cannabinoid, estimated to be 10 to 20 times stronger than Delta 9 THC. While it doesn’t bind as aggressively as THCp, it still delivers a notably intense experience.
What to expect from a THCh high:
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A strong psychoactive effect with a more uplifting, giggly high
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Deep relaxation paired with heightened sensory perception
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A slightly smoother but still powerful hit compared to THCp
Since these cannabinoids are significantly more potent than traditional THC, even experienced users may want to start slow to gauge their tolerance.
Our Top 8 Strongest Disposable Vapes for an Unforgettable 420
Without further ado, here are eight of our strongest disposable vapes to make sure that your 420 is one for the history books.
THCp Granddaddy Purp Disposable Vape
When 420 rolls around, some people want to go big, and some people want to completely sink into their surroundings.
If you love kicking back and fully embracing the relaxation side of 420, this Granddaddy Purp THCp disposable is your best bet.
What to Expect: From the first hit, expect a deep wave of euphoria to wash over you, melting tension and stress almost instantly. This is the kind of high that locks you to the couch, perfect for when you’re done celebrating and ready to sink into pure comfort.
Flavor Profile: Rich grape and berry flavors dominate, with a smooth, slightly earthy finish that keeps each hit tasty and satisfying.
Best Use: Best for late-night 420 sessions when you’re winding down after a day of celebrating. Whether you’re watching a classic stoner movie, chilling with music, or just vibing in deep relaxation, this vape keeps the good times rolling until you’re ready to pass out blissfully.
THCp White Runtz Disposable
Some 420 sessions are about finding the perfect balance. You want to get high enough to feel amazing, but not so high that you’re completely out of commission. White Runtz, packed with THCp, delivers a strong, long-lasting buzz that’s both uplifting and relaxing, making it perfect for an all-day 420 celebration.
What to Expect: This White Runtz vape kicks off with a strong head high, lifting your mood and leaving you giggly and stress-free. As the session continues, a relaxing body buzz sneaks in, keeping you chill without knocking you out.
Flavor Profile: Sweet and creamy with a hint of citrus, this vape tastes like candy with a touch of earthiness, making every puff smooth and flavorful.
Best Use: Perfect for early-evening 420 celebrations, this vape keeps you in a great mood without leaving you too sluggish. Whether you’re hanging with friends, playing video games, or enjoying some snacks, it delivers a strong but functional high.
THCp Strawberry Cough Disposable Vape
420 is about celebrating, laughing, and making the most of the day. If you need a vape that keeps you energized, social, and feeling fantastic, Strawberry Cough is the ultimate sativa. This THCp disposable is a top contender when it comes to lively 420 celebrations.
What to Expect: Expect an instant mood boost with a wave of euphoria and creative energy. This vape keeps your mind sharp and your body light, making it ideal for social gatherings, outdoor adventures, or just staying engaged throughout 420. If you’re looking for a high that keeps you talking, laughing, and feeling uplifted, this is it.
Flavor Profile: Bright, sweet strawberry flavors burst through on the inhale, with a smooth, slightly herbal exhale. The balance of juicy fruitiness and light earthiness makes this vape deliciously refreshing.
Best Use: Best for daytime 420 celebrations, group smoke sessions, or any activity where you want to stay alert and engaged. Whether you’re hitting up a festival, playing games, or just enjoying a sunny afternoon outside, Strawberry Cough ensures you stay lifted and loving every moment.
THCp Northern Lights Disposable Vape
If you plan to go all out on 420 and need something to help you come down smoothly, this Northern Lights THCp disposable vape is the ultimate nightcap. This legendary indica, supercharged with THCp, brings an ultra-potent body high that’s perfect for ending the night on a blissfully hazy note.
What to Expect: A strong body buzz takes over almost immediately, releasing any tension from the day’s festivities. A calming head high follows, leaving you peaceful, relaxed, and ready to drift into the perfect post-420 sleep.
Flavor Profile: Earthy and piney with a slight sweetness, this vape has a classic cannabis taste with a fresh herbal twist.
Best Use: Ideal for closing out 420 with a deeply relaxing final session. If you’re looking for a vape that will help you fully decompress and melt into bed, Northern Lights is the perfect night-ender.
THCh Blue Cheese Disposable Vape
420 isn’t just about getting high, it’s about the experience, and this Blue Cheese THCh vape brings a unique, flavorful twist to the mix. This powerful indica infused with THCh delivers a strong but smooth high, ideal for chilling out while still enjoying the moment.
What to Expect: The high builds gradually, easing you into a state of deep relaxation without making you feel foggy. A heavy body buzz sets in, making you feel weightless yet completely at ease.
Flavor Profile: A bold mix of blueberries and funky cheese, creating a creamy, rich flavor that’s unlike anything else. The balance of sweet and savory makes each hit unique and unforgettable.
Best Use: Best for laid-back 420 sessions with friends or solo chilling. If you enjoy sitting back, having deep conversations, and vibing out, this vape keeps things calm yet engaging.
THCh Cheetah Piss Disposable Vape
420 is a full-day event, and sometimes you need a vape that keeps you moving. Cheetah Piss is the perfect party strain, delivering high energy and social vibes to keep your 420 session fun and engaging.
What to Expect: This Cheetah Piss THCh vape hits fast and hard, giving you an instant head rush and a euphoric boost. Expect to feel talkative, giggly, and energized, making it great for group settings and outdoor festivities.
Flavor Profile: Citrusy and creamy with a touch of earthiness, this vape tastes sweet but balanced, with a smooth and light exhale.
Best Use: Best for social 420 events like parties, festivals, or group smoke sessions. If you want a high that keeps the conversation flowing and the vibes high, this is the perfect pick.
THCh Green Goblin Disposable Vape
420 isn’t just about chilling. Sometimes you want to stay productive, active, and fully engaged. Green Goblin is the ideal daytime vape, giving you an energizing and clear-headed high that lasts.
What to Expect: This vape hits with an instant wave of energy, leaving you motivated, focused, and uplifted. Expect a strong cerebral buzz with a creative spark, keeping you engaged in whatever activity you’re enjoying.
Flavor Profile: Bright citrus with fresh herbal notes and a mild earthiness, giving it a crisp and refreshing taste.
Best Use: Best for daytime 420 celebrations when you want to stay energized and engaged. Whether you’re hitting a festival, playing games, or just enjoying the outdoors, Green Goblin keeps you buzzing and productive.
THCh Skywalker OG Vape
The Skywalker OG THCh disposable vape is perfect for when 420 has left you completely spent, and you just need to relax. This heavy indica delivers deep euphoria and physical comfort, making it the ultimate strain for full-body relief.
What to Expect: A warm, relaxing buzz sets in immediately, easing your mind and body into a state of deep, peaceful euphoria. This is one of the strongest indica vapes, perfect for melting into your surroundings.
Flavor Profile: Spicy herbal notes with sweet citrus hops, followed by a bold, earthy exhale that lingers nicely on the palate.
Best Use: Best for closing out 420 when you’re ready to fully relax and let go. Whether you’re enjoying a final smoke session with friends or just preparing for deep sleep, Skywalker OG delivers a powerful, long-lasting calm.
Don’t forget that starting on the first of April, Mellow Fellow will offer a full three weeks of discounts and savings on these THCp and THCh vapes, and more!
What Makes Mellow Fellow's High-Potency Vapes Stand Out
At Mellow Fellow, we take high-potency vapes seriously. Whether you're gearing up for a full-throttle 420 celebration or looking for something that delivers a long-lasting, ultra-potent high, our THCp and THCh disposables are crafted with precision, safety, and quality in mind.
Unmatched Quality and Safety Standards
We don’t just meet industry standards, we set them. Every disposable vape in our lineup undergoes rigorous lab testing to ensure accurate cannabinoid content, purity, and a completely safe experience. When you’re inhaling something this potent, you deserve to know it’s clean, pure, and consistent.
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Third-Party Lab Testing: Each batch is tested for potency, pesticides, heavy metals, and residual solvents to guarantee purity and safety.
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Compliance with State and Federal Regulations: Our vapes contain no harmful additives or contaminants, ensuring peace of mind with every puff.
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Ingredient Integrity: We source our cannabinoids and terpenes from premium, organically grown hemp, free of synthetic fillers or unnecessary additives.
From the relaxing Granddaddy Purp and Northern Lights to the uplifting Green Goblin and Strawberry Cough, every vape in our collection is crafted for maximum potency and consistency.
Precision Cannabinoid Blending for Maximum Potency
How our vapes are made is what sets them apart from the competition. Our proprietary mixing techniques allow us to create precise cannabinoid ratios that deliver intense effects, long-lasting highs, and exceptional flavors.
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Tailored Cannabinoid Blends: By fine-tuning THCp and THCh ratios, we ensure each vape delivers the strongest and most balanced effects possible.
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Advanced CO2 Extraction: We use cutting-edge CO2 extraction to preserve cannabinoid integrity while eliminating impurities, giving you a clean, potent experience.
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Enhanced Terpene Profiles: Unlike many high-potency vapes, we carefully reintroduce natural terpenes after extraction to boost flavor and maximize effects.
This meticulous process allows us to create powerful, flavor-packed disposables like Skywalker OG for deep relaxation, Cheetah Piss for social energy, or White Runtz for a balanced, all-day high. No matter what kind of 420 experience you're after, we've got a high-potency vape designed just for you.
Let’s now help you pick the right vape to make the most out of your 420 festivities.
Picking the Right High-Potency Vape for Your 420 Celebration
420 is all about celebrating weed in the best way possible, and the right vape can take your experience to the next level. Whether you're looking for big energy for a party, deep relaxation for a movie marathon, or something in between, picking the right high-potency disposable comes down to a few key factors.
Potency
The first thing to consider is just how strong you want your vape to be. THCp is the most potent cannabinoid available, packing an ultra-powerful high that lasts longer and hits harder than Delta 9 THC.
It’s best for those who already have experience with strong cannabis products and want a vape that delivers a deep, immersive high. If you’re looking for an intense couch-lock session, something like Northern Lights or Skywalker OG with THCp will absolutely do the trick.
THCh, on the other hand, is still much stronger than regular THC but tends to have a slightly lighter, more functional high. It’s great for those who want potency without being totally knocked out. If you’re planning to stay social and keep the good vibes going, a THCh hybrid like Cheetah Piss is a great choice.
If you’re new to high-potency vapes, starting with THCh over THCp is probably the safer move. You can always go stronger next time!
Strain
Strains make a huge difference in how your 420 plays out. If you grab a strong indica, expect to feel relaxed, sedated, and blissfully spaced out. These are the go-to choices for low-key sessions, nighttime use, and full-body relaxation.
If your idea of a perfect 420 is getting comfy, putting on a classic stoner movie, and melting into the couch, then a heavy indica like Granddaddy Purp or Blue Cheese is exactly what you need.
Sativas, on the other hand, tend to boost energy, spark creativity, and keep you engaged. These are perfect for daytime festivities, 420 events, and social settings.
If you’re heading to a cannabis festival, a park smoke session, or just want to keep the laughs going with friends, a sativa like Strawberry Cough or Green Goblin will keep you elevated and in the moment.
Hybrids offer a balance between the two, making them versatile choices for an all-day 420 celebration. If you’re looking for something strong but not overwhelming, White Runtz is a solid middle ground.
Desired Effects for Festivities
Not all 420 plans are the same, so it’s important to match your vape to the kind of celebration you’re planning. If you’re going to be out and about, socializing, and attending events, you don’t want to accidentally hit something too heavy and find yourself unable to move.
Instead, a lighter THCh sativa like Strawberry Cough will keep you energized, happy, and talkative throughout the day.
If your 420 is more about kicking back with snacks, dim lights, and a movie marathon, you’ll probably want an indica THCp vape like Skywalker OG or Northern Lights to lock you into full relaxation mode.
Hybrids are great for mixed plans—maybe you’re starting the day being social but planning to wind down later. A hybrid like White Runtz or Cheetah Piss lets you ride the waves of both energy and relaxation throughout the day.
Flavor
Let’s be real, flavor matters. The best vapes don’t just hit hard, they taste good too. If you love fruity, candy-like flavors, Strawberry Cough or White Runtz will give you sweet, creamy, and smooth hits.
For those who enjoy classic, earthy cannabis flavors, Skywalker OG or Northern Lights deliver a woody, herbal taste with hints of spice.
Some vapes go bold and unique, like Blue Cheese, which combines blueberry sweetness with a funky, creamy twist. If you like citrus-forward flavors, Cheetah Piss brings a mix of tangy fruit with a hint of earthiness.
Your flavor preference won’t change how high you get, but it will make the experience way more enjoyable.
Other Things to Consider
Here are some additional considerations to keep in mind when making your choice:
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Duration of Effects: THCp tends to last longer than THCh, so if you’re looking for an all-day ride, a THCp vape will keep you lifted longer. If you prefer something strong but slightly shorter-lived, THCh might be a better fit.
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Discreetness: All of these vapes are compact and easy to use, but some strains have stronger, more pungent aromas than others. If you’re trying to keep things low-key, go for something with a milder smell, like White Runtz.
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Battery & Convenience: These disposables are ready to go right out of the box, so you don’t have to worry about charging or refilling. Just take a hit and enjoy the ride.
Enhancing Your 420 Vape Experience
A high-potency disposable vape can take your 420 celebration to the next level, but getting the most out of it requires a little know-how.
THCp and THCh vapes hit harder and last longer than standard THC, so a thoughtful approach to dosing, usage, and care will ensure you get the best possible experience. Whether you’re planning a chill night in or a full-day celebration, here’s how to maximize every hit.
Best Practices for High-Potency Vapes
Let’s go over some best practices for high-potency vapes, so you can blast off to the stratosphere and see the world from a new perspective without feeling like you're stranded in outer space.
Start Slow, Even If You’re Experienced
THCp and THCh aren’t your average THC vapes. They pack way more punch, and effects can creep up on you. Even seasoned users should start with just one or two hits and wait 20 to 30 minutes before deciding to take more. Overdoing it too fast can turn a great 420 into an accidental nap.
Store Your Vape Properly
To keep your vape in top condition, store it upright in a cool, dry place, away from direct sunlight and extreme heat. Leaving it in a hot car or in direct sunlight can cause oil leakage or degrade potency. If you want your vape to hit smoothly every time, proper storage is key.
Take Slow, Controlled Hits
Big, deep inhales can be overwhelming with high-potency vapes. Instead, take slow, moderate pulls to avoid harshness and maximize flavor. Since THCp and THCh effects can last longer than traditional THC, you don’t need to chain-hit it, so give it time to settle in.
Keep Your Battery Charged
While disposables are designed for convenience, some high-capacity vapes come with rechargeable batteries. If your vape stops hitting properly, a quick charge might bring it back to life. Make sure your device is ready to go before your 420 festivities kick off.
Pairing Suggestions for 420 Activities
Not all highs are the same, and pairing the right vape with the right activity can take your 420 celebration to another level. Whether you’re in the mood for a high-energy day, a creative session, or pure relaxation, there’s a perfect THCp or THCh vape for the moment.
For Socializing, Parties, and Events
If you’re spending 420 out with friends, attending events, or just vibing at a party, you’ll want a high that keeps you upbeat, talkative, and engaged. Sativa or hybrid THCh vapes are perfect for staying social and energized without feeling too heavy.
Best Picks: Strawberry Cough for its uplifting, giggly high or Cheetah Piss for a fun, talkative buzz.
For Creativity and Deep Thinking
Looking to unlock your inner artist, write some poetry, or just let your mind wander in the best way possible? A vape with a cerebral, slightly dreamy effect can help spark creativity and inspiration.
Best Picks: Green Goblin for a clear, focused mental buzz or White Runtz for a balance of relaxation and creative energy.
For Movie Marathons and Chill Sessions
420 wouldn’t be complete without classic stoner comedies, animated favorites, and trippy visuals. If your plan is to kick back with snacks and zone into your favorite movies, an indica-dominant THCp vape is exactly what you need.
Best Picks: Granddaddy Purp for its heavy relaxation or Northern Lights for a blissful, dreamy vibe.
For Outdoor Adventures
Some people spend 420 hiking, skating, or just enjoying the fresh air, and the right vape can enhance the experience without slowing you down. You’ll want a strain that keeps you alert, motivated, and ready to take in the scenery.
Best Picks: Strawberry Cough for an energetic buzz or Green Goblin for a sharp, focused high.
For Full-On Couch-Lock and Relaxation
If you’re looking to melt into your couch and fully surrender to relaxation, a high-potency indica is the way to go. Whether you’re enjoying a deep conversation, zoning out to music, or just staring at the ceiling with a smile on your face, these vapes will take you there.
Best Picks: Skywalker OG for a powerful euphoric body high or Blue Cheese for chill vibes with mental clarity.
Ready to Elevate Your 420 Experience?
420 is all about celebrating cannabis in the best way possible, and nothing takes your experience to new heights like high-potency disposable vapes.
With cannabinoids like THCp and THCh delivering effects far stronger than standard THC, these vapes are perfect for both high-energy festivities and laid-back relaxation. From the uplifting buzz of Strawberry Cough to the full-body bliss of Skywalker OG, Mellow Fellow has crafted a collection that caters to every kind of celebration.
Each vape is lab-tested for purity, potency, and safety, ensuring a clean, powerful experience every time. Whether you are looking for a euphoric boost, creative inspiration, or total relaxation, Mellow Fellow has a high-potency disposable designed just for you.
Check out our full collection today and make this 420 one to remember with Mellow Fellow’s exclusive 420 deals!
Frequently Asked Questions
How Do THCp and THCh Compare to Delta 9 THC?
THCp is up to 33 times stronger than Delta 9 THC, delivering a more intense and long-lasting high. THCh is about 10 to 20 times stronger, offering a potent but slightly smoother experience.
Are High-Potency Vapes Suitable for Beginners?
Beginners should start with a low dose and opt for THCh vapes over THCp, as they are slightly milder. Even experienced users should take it slow with these potent cannabinoids.
How Long Do THCp and THCh Vapes Last?
Effects from THCp and THCh can last significantly longer than Delta 9 THC, often ranging from four to eight hours, depending on dosage and individual tolerance.
Can I Use These Vapes Discreetly?
Yes, Mellow Fellow’s disposables are compact and portable, making them easy to use discreetly. Some strains have stronger aromas, so consider a milder-smelling option like White Runtz if needed.
What’s the Best Vape for a Social 420 Celebration?
For socializing, choose an uplifting strain like Strawberry Cough or Cheetah Piss, which promote energy, conversation, and good vibes without making you too sluggish.
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