What is THCv?

2 comments May 17, 2023

THCv stands for tetrahydrocannabivarin, which is a cannabinoid structurally similar to THC (Tetrahydrocannabinol), except for a shortened side chain. THCv, or THC-v, is an alternative cannabinoid that comes with unique effects and benefits that set it apart from THC and CBD.

THCv is a minor cannabinoid that is typically found in relatively low concentrations in most strains. However, when THCv is extracted and bred in higher concentrations, it produces a non-psychotropic effect that comes with unique therapeutic effects from its cousin, THC.

A substance that is psychotropic affects your mental state and your ability to cognitively function, but THCv does not do this.

THC vs. THCv, What are the Differences?

While they may sound similar, THC and THCv have different pharmacological profiles. Key differences between THC and THCv include:

  • Psychoactive effects: When we think of THC, we associate it with a “high” (psychotropic) feeling that comes with our D9 consumption. THCv is psychoactive since it passes your blood-barrier but does not produce a “high” (non-psychotropic) effect, and is known to produce a focused and alert state of mind instead.
  • Effects on appetite: THC-v gives users the effect of an appetite suppressant, which is the opposite of the munchies we may be used to with THC products. This is why some people call THCv “diet weed”
  • Receptor binding: Both THC and THCv interact with the central nervous system’’s CB1 and CB2 receptors. Evidence from a recent study shows that as THC activates and boosts the CB1 receptor, THCv suppresses the CB1 and CB2 receptor. Therefore, THC and THCv has an opposite effect on the body, as we see in the different ways these two compounds impact our appetite.
  • Potential therapeutic effects: Both THC and THCv display therapeutic effects in different areas. THC has been studied for pain-relieving, anti-inflammatory, and anti-nausea effects, while THCv is being studied for opportunities for use with those experiencing obesity, diabetes, and seizures. 

Related Article: "Rare Cannabinoids: Full Guide"


What Does THCv Do?

THCv effects include clear-headedness, motivation, and a suppressed appetite, which is how THCv received the nickname “weederall”. THCv as a standalone compound is known primarily for its non-psychotropic, diet suppressing effects.

In newer studies, scientists have explored the possibility of THCv having a positive effect on individuals with diabetes, epilepsy, anxiety, Alzheimers, and bone density.

Something to keep in mind when it comes to THCv is that it is typically found in trace levels, and when blended with other cannabinoids you may not receive the pure THCv effects that you read about online.

THCv is an emerging cannabinoid that we are starting to understand and unlock new capabilities with, and the initial results are an exciting look into the universe of capabilities with the cannabis plant.

THCv: Chemical Composition and Basic Properties

Tetrahydrocannabivarin is a cannabinoid found naturally in the cannabis plant. THCv, although similar in molecular structure to the beloved and well-known THC, boasts a shorter atom side chain that makes it similar but different in an important way. 

THCv isn’t technically psychoactive - meaning it won’t get you high. It can act as a psychotropic, with high doses causing a buzz. Without a high, however, THCv can still provide effects like elevated focus and alertness, acting as a true non-intoxicating sativa with energizing and invigorating effects. 

The buzz surrounding THCv may be due to the potential this cannabinoid has as an appetite suppressor, showing promise as an aid for weight management and nutrition habits. 

With a nickname like “diet weed”, it’s no surprise that people are turning toward THCv in order to enjoy the effects of cannabis without raiding the snack cupboard.

The Effects and Benefits of THCv

THCv’s effects mainly attract people seeking two things: a less intense THC experience or a munchies-free experience. THCv’s more moderated psychoactive effects keep you clear-headed and alert, while the hunger-curbing effects allow you to enjoy cannabinoids without ordering pounds of take-out. 

THCv’s potential as an appetite suppressor and metabolism enhancer is a potential game-changer for those who use cannabinoids as a therapeutic aid. With science hinting at its possible application in managing various medical conditions, it’s beginning to gain traction in medical and recreational cannabis communities.

Understanding Its Effects

THCv works by activating CB1 and CB2 receptors in the body, which are found in the endocannabinoid system. The endocannabinoid system is responsible for regulating a wide range of physiological functions, from immune function and mood to pain and perception of time. 

When cannabinoids like THCv come in contact with the receptors in this system, a variety of effects can break loose. 

THCv is a special case since psychoactive cannabinoids usually have to act as agonists in order to be psychoactive. THCv is an antagonist, but a high enough dose of it can reverse those effects and make it psychoactive.

What is THCv Good For: Medical and Wellness Applications

While more research is needed to define what exactly THCv does in the body, initial reports seem to identify potential in THCv’s energizing effects in therapeutic areas like seizure reduction, emotional regulation, and reduced cravings for addiction (mainly the addiction to food). 

THCv is being studied for its potential use as a management aid in various conditions, including diabetes, pain, weight loss, and even mental health issues. 

It is important to note that the scientific community still has a lot to learn about this cannabinoid, and before using THCv, it’s best to speak to a medical professional.

THCv vs. THC

THCv and THC are chemical cousins, meaning they share a similar molecular structure. However, a difference in an atom chain bond (specifically, a shorter one in THCv than in THC) causes this cannabinoid to interact differently with the endocannabinoid system, leading to very different effects. 

When it comes to chemistry, even the slightest variation can make a world of difference. 

What is THCv in Weed: Strains and Content

Most strains have trace amounts of THCv since it’s naturally found in tiny amounts in the cannabis plant. However, there are some strains that boast a higher amount (which is great knowledge if you’re looking to enjoy the effects of THCv). 

Strains like Durban Poison, Girl Scout Cookies, Jack the Ripper, Tangie, and Doug’s Varin are popular strains with high traces of THCv. 

THCv and Its Place in Cannabis Research

2 people holding a bottle of Mellow Fellow's Wellness Tincture.

The new era of cannabis and cannabinoids is opening up a world of opportunity for the scientific community as they research the applications and effects of different cannabis compounds. 

THCv holds a special place in this industry, standing tall as the only known cannabinoid that manages to keep munchies at bay. 

It’s important to continue to research this cannabinoid, as most experiences are yet to happen in clinical settings. The full potential is an exciting prospect for those seeking to manage weight or conditions like diabetes, and only time will tell whether THCv is a worthy therapeutic aid.

How Strong is THCv?

When we talk about the strength of a new cannabinoid, each of us may have different definitions of strong. Factors like THC tolerance, frequency of use, the body’s metabolism, and the presence of other cannabinoids will always play a role that makes each cannabis experience unique.

When considering how strong THCv is, what first comes to mind is the psychoactivity and intensity of the “high” effect produced by THC products. In low doses, THCv’s CB1 antagonist properties mean that it is non-psychotropic. However, when we start taking THCv in higher doses, it can switch and start behaving more like THC, giving a psychoactive buzz. 

If you are wondering in general how strong THCv is in terms of potency, THC-v is not as strong as a D9 THC product and not as benign as a CBD product. Early studies suggest THCv is a quarter as potent as THC products, however when combined with other cannabinoids this may change.

When it comes to trying a new cannabinoid, we always recommend starting low and slow, increasing your dose gradually as you determine what is right for you and your needs.

Will THCv Fail a Drug Test?

Drug tests are tricky when it comes to testing Marijuana products, as the Mellow Fellow team has examined in the past with other cannabinoids.

Alternative cannabinoids may not specifically have THC, however, when a drug test examines the presence of a Marijuana product, it’s likely that an alternative cannabinoid will show up.

THC-v and other cannabinoids show up because drug tests detect the presence of THC metabolites. With that in mind, we would not recommend consuming THC-v if you have a drug test on the horizon. Better safe than sorry!

Related Article: "HHC vs CBN: Which Will Make You Fail A Drug Test?

da vinci clarity What is THCv

Where to Find the Best THCv Products

Mellow Fellow offers THC-v products in prerolls, gummies, disposables, cartridges, cereal bars, diamonds, and more. 

We highly recommend Mellow Fellow’s Clarity Blend for a focusing experience. Known for being high on energy and low on anxiety, this blend is a trademark THCv and HHC blend that the Mellow Fellow team blended to bring the best of THC-v to you.

When you're looking to take your productivity to the next level, or if you want to find a more natural way to find focus and peace of mind, da Vinci's Clarity Blend is the perfect solution.

If you are looking for more of an energizing and stimulating experience, look no further than Mellow Fellow’s Charged Blend for a festive and invigorating effect. The Charged blend is designed to get you over any hump in your energy, getting you going in a way that makes you feel a little more vigorous with each puff.

Final Thoughts

It’s best to stay informed as the worlds of THCv and cannabinoids continue to expand in popularity and demand, whether in recreational or medical circles. Knowledge is the key to unlocking the full potential of the experience this cannabinoid can provide, and responsible use is always your best bet.

Frequently Asked Questions: What is THCv?

How Does THCv Compare to CBD in Terms of Health Benefits?

CBD’s effects are known to be calming and relaxing, while THCv’s effects are known to be energizing and invigorating. 

Are There Any Potential Side Effects or Risks Associated with THCv?

More research is needed in order to identify specific side effects or risks associated with the use of THCv. 

How Can Consumers Identify Cannabis Products High in THCv?

Strains like Durban Poison, Girl Scout Cookies, Tangie, and Jack Herer are known to have high amounts of THCv. 

What Does THCv Do to the Body?

THCv may produce a buzz and typically energizing effects, as well as reduce cravings and help regulate the metabolism.


  • Sir Adam M. May 24, 2023 at 9:47 pm

    The clarity blend I always come back to it. It tends to tantalize my senses, and being a Insta-anxiety be gone weapon I give it five of age shaven virgin asses up.

  • Sir Adam M. May 24, 2023 at 9:47 pm

    The clarity blend I always come back to it. It tends to tantalize my senses, and being a Insta-anxiety be gone weapon I give it five of age shaven virgin asses up.

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