What Is HHC? What You Need to Know
Quick Answer: HHC, or hexahydrocannabinol, is a hydrogenated form of THC that offers effects many describe as sitting between Delta 8 and Delta 9 THC. It is more stable, often provides a clear-headed experience, and varies depending on isomer ratios. While federally legal, state laws differ, and drug testing may detect it.
Back in 1944, American chemist Roger Adams first created hexahydrocannabinol by adding hydrogen molecules to THC. At the time, it was little more than a scientific curiosity. Fast forward to today, and his discovery is suddenly in the spotlight again.
Walk into almost any vape shop and you’ll spot HHC products sitting right beside Delta 8 and Delta 9. That leaves many people asking the same question you might be wondering now: what is HHC, and how does it stack up against the THC you already know?
Key Takeaways
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HHC is a hydrogenated cannabinoid first created in 1944, now widely available in vapes, edibles, and other hemp products.
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Effects typically feel more functional and balanced than Delta 9, lasting two to three hours when vaped and up to six hours when consumed as edibles.
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Compared to other cannabinoids, HHC is generally milder than Delta 9, stronger than Delta 8, more predictable than THC-O, and less potent than THCp.
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The safety profile shows no major concerns in preclinical testing, though more studies are needed, and user reports highlight consistent stress and sleep support.
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To experience HHC safely, choose transparent brands with Certificates of Analysis, start with low doses, and check local legality before purchasing.
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Mellow Fellow provides rigorously tested HHC products, ensuring consistency, safety, and reliability for every customer.
HHC's Molecular Structure
Hexahydrocannabinol, or HHC, looks very similar to THC at the molecular level. In fact, both share the same formula: C₂₁H₃₀O₂. The big difference comes from a process called hydrogenation. This process adds extra hydrogen atoms to THC, removing the double bonds in its structure.
The result is a molecule that is fully saturated with hydrogen and much more stable than THC. That stability is why researchers often call HHC the most durable form of THC.
This change in structure produces two types of HHC, known as isomers.
One isomer, called 9R-HHC, binds strongly to your body’s CB1 receptors in a way that is almost identical to Delta 9 THC. The other, 9S-HHC, also binds but much less effectively, meaning it contributes far less to the overall effects you feel.
Why Isomer Ratios Matter
The mix of these two isomers explains why HHC products can feel so different from one another. A study published in ACS Chemical Biology tested more than 60 commercial HHC products and found wide variation in isomer ratios.
Some contained mostly the more active 9R form, while others leaned heavily toward the less active 9S form. This is why two HHC vapes or edibles with the same cannabinoid content can give you completely different experiences.
How Mellow Fellow Ensures Consistency
At Mellow Fellow, our team of PhD chemists carefully manages the hydrogenation process to keep isomer ratios consistent in every batch. All of our HHC products, from vape cartridges to disposables, undergo strict third-party lab testing.
These reports verify not only the total HHC content but also the specific isomer ratios, so you know exactly what you’re getting each time - the Purple Punch HHC Disposable is always a fan-favorite thanks to its sweet flavor and ability to help with rest and relaxation.
How HHC Affects Your Body
HHC delivers an experience many describe as sitting comfortably between Delta 8 and Delta 9 THC. The effects are often clear-headed and uplifting, with less of the anxious edge that can sometimes come with stronger THC products. Users commonly report a light euphoria paired with a calm, steady mindset.
Researchers believe this difference comes down to how HHC interacts with your cannabinoid receptors. It activates the same receptors as THC but triggers slightly different responses inside your cells. These variations may explain why people often feel relaxed and focused without side effects like paranoia or racing thoughts.
Onset and Duration of Effects
The way HHC feels depends a lot on how you consume it. When vaped, such as in our Strawberry Cough HHC Cartridge, effects usually begin within 5-10 minutes, peak around the 30-45 minute mark, and taper off after 2-3 hours. Edibles, such as the M-Fusions HHC Gummies, follow a slower timeline: onset at 30-60 minutes, peak effects around 2-3 hours, and a total duration of 4-6 hours.
What Users Typically Experience
Many people say HHC gives them a more functional high than Delta 9 THC, allowing them to stay productive while still enjoying a gentle euphoria and relaxation.
Another interesting aspect, according to user reports, is that HHC may not build tolerance as quickly as traditional THC. Some regular consumers say they can use it daily without constantly needing to increase their dose, though formal studies on this are still ongoing.
The Production Process: From Hemp to HHC
Although HHC does occur naturally in cannabis, it’s found in such tiny amounts that direct extraction isn’t practical. Instead, modern production relies on converting more abundant cannabinoids like CBD into HHC through a method called hydrogenation. This is the same basic process used in the food industry to turn vegetable oil into margarine, though here it’s carefully adapted for cannabinoids.
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The process starts with hemp-derived CBD isolate, which is combined with hydrogen gas and a catalyst such as palladium, platinum, or nickel.
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Controlling the temperature is key. Lower temperatures favour the formation of the more active 9R-HHC isomer, while higher temperatures can produce more of the less active 9S form. This reaction is carried out in a controlled, oxygen-free environment to prevent unwanted chemical changes.
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Once the conversion is complete, the crude HHC mixture goes through several purification steps. Chromatography helps separate HHC from leftover materials, and distillation removes solvents or catalyst residues.
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The product is then refined further until it reaches pharmaceutical-grade purity, often exceeding 95%.
This careful process ensures a cleaner, more consistent final product. For consumers, that means HHC vapes, edibles, or cartridges made by reputable manufacturers are not only safer but also more predictable in their effects.
Our complete cannabinoid guide explains how HHC fits into the broader spectrum of hemp-derived compounds.
HHC vs. Other Cannabinoids: A Detailed Comparison
To understand where HHC fits, it helps to see how it compares to better-known cannabinoids. Each one interacts with your body in slightly different ways, and those differences shape the experience.
HHC vs. Delta 9 THC
The active 9R-HHC isomer is estimated to have about 70-80% of Delta 9’s potency. While Delta 9 is known for producing intense highs that can sometimes feel overwhelming, HHC is often described as more functional and easier to handle.
Many people report that it comes with less anxiety or paranoia, offering a clearer mental state. The trade-off is duration: when vaped, HHC typically lasts 2-3 hours, compared to Delta 9’s 3-4 hours. Many customers who find traditional THC too intense have discovered that our Blueberry OG HHC Disposable provides the perfect middle ground.
HHC vs. Delta 8 THC
HHC generally feels stronger than Delta 8 but milder than Delta 9. Delta 8 is often associated with a body-heavy, calming effect, while HHC provides a more balanced experience that combines both mental uplift and physical relaxation.
For this reason, many users consider HHC better suited for daytime, while Delta 8 is often chosen for winding down in the evening. If you're curious about Delta-8, our comparison guide breaks down the differences in detail - and for those interested in trying this cannabinoid, our Sour Diesel Delta 8 Vape is a great place to start.
HHC vs. THC-O
THC-O is different because it’s a prodrug, meaning it needs to be metabolized by your body before becoming active. Once it is, it can be two to three times stronger than Delta 9 and may produce effects that feel closer to psychedelics.
HHC, on the other hand, is active right away and stays within the familiar cannabis effect range. This makes it far more predictable for everyday use compared to THC-O’s intensity.
HHC vs. THCp
THCP, discovered in 2019, binds to CB1 receptors with about 33 times the strength of Delta 9 THC.
Its extreme potency means it appeals mostly to people with very high tolerance levels. HHC, on the other hand, offers a gentler, more manageable experience that suits regular use.
For most users, it strikes the right balance of enjoyment without tipping into overwhelming effects. Our THCp collection is available for those seeking maximum potency
Safety Profile and Current Research
The safety of HHC is still being studied, but recent preclinical work has provided some useful insights. A 2022 in vitro safety assessment by Collins and colleagues tested hemp-derived HHC across several standard pharmaceutical safety screens.
One important area was cardiac safety. Researchers used a hERG patch-clamp assay, which checks for potential interactions with ion channels linked to irregular heart rhythms. HHC showed no concerning activity at typical test concentrations, suggesting a low risk for heart-related side effects.
The study also looked at human liver cells and found no evidence of toxicity in hepatocyte viability assays. This indicates that normal use levels of HHC are unlikely to cause liver damage. Overall, the findings suggest that HHC is generally safe human consumption when used responsibly.
Our customers consistently report that products like our Master Blends collection provide predictable effects without unwanted surprises.
Finding Your Perfect HHC Product: A Curated Selection Guide
Choosing the right HHC product can shape your experience, whether you’re starting out or looking to fine-tune how you use it. Below are some options from Mellow Fellow designed for different needs.
For the HHC Newcomer: Start Here
The Purple Punch HHC 2ml Disposable is a popular choice for first-time users. This indica-leaning blend provides about 600 pulls of grape-flavored vapor. With terpenes like beta-caryophyllene and linalool, it supports relaxation while avoiding the anxious edge sometimes linked with stronger cannabinoids. Each puff delivers a consistent dose, and the rechargeable design prevents waste or hardware issues.
For Daytime Functionality: Energy Without Impairment
The Strawberry Cough HHC Cartridge is sativa-dominant, combining pinene and limonene for an uplifting effect. Users often describe clear-headed euphoria, improved focus, and a smooth strawberry flavor. Effects last two to three hours, making it a good fit for creative work or social activities. The ceramic coil maintains even heat, preserving both flavor and potency.
For Maximum Value: The Bundle Approach
The HHC 1ml Cartridge Bundle - 2 Pack is designed for experienced users who want variety at a lower cost. The bundle pairs different strains, allowing you to try HHC in both energizing and relaxing formats while saving compared to buying cartridges separately.
For Extended Sessions: Large Format Options
The Pineapple Express HHC 2ml Disposable offers a larger capacity for longer-lasting use. This hybrid blend balances mental uplift with physical calm, making it versatile for any time of day. Its tropical pineapple flavor is a favorite among those who prefer fruity notes over traditional hemp taste.
For Precise Dosing: Edible Excellence
The HHC M-Fusions Fruit Punch Gummies provide 50mg of HHC per gummy, infused directly for consistent effects. Onset typically takes 30-60 minutes, with peak effects around two to three hours and a total duration of four to six hours.
The experience is more body-focused and sedating than vaping, making gummies best suited for evenings. They’re also vegan and gluten-free. Beginners should start with half a gummy and wait at least two hours before considering more.
The Stability Advantage: Why HHC Lasts Longer
One of HHC's most significant advantages over other cannabinoids lies in its exceptional stability. The hydrogenation process that creates HHC eliminates the double bonds that make THC vulnerable to oxidation and degradation. This resistance to breakdown means your HHC products maintain their potency far longer than traditional THC products.
While Delta 9 THC and CBD products can lose 20-30% of their potency within 6 months under normal storage conditions, HHC products maintain their strength for over a year when stored properly.
This stability extends to temperature tolerance as well - HHC withstands the high temperatures involved in vaping without breaking down into potentially harmful compounds. This thermal stability makes it ideal for use in disposable vapes and cartridges that may experience temperature fluctuations during shipping and storage.
For retailers and consumers alike, this stability offers practical advantages. Products don't need special storage conditions beyond basic cool, dark environments. There's no rush to consume products before they degrade.
Legal Considerations and Current Status
The legal status of HHC in the United States is complicated and varies by state. At the federal level, the 2018 Farm Bill legalized hemp-derived products containing no more than 0.3% Delta 9 THC on a dry-weight basis.
Because HHC can be derived from hemp-based CBD and is not specifically listed in the Controlled Substances Act, it is generally considered federally legal.
At the state level, however, the picture is far less uniform. As of 2025, states fall into several categories:
States Where HHC Is Legal
Hemp-derived HHC is legal in Alabama, California, Connecticut, Florida, Georgia, Indiana, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Nebraska, New Jersey, New Mexico, North Carolina, Ohio, Oregon, Pennsylvania, South Carolina, South Dakota, Tennessee, Virginia, and West Virginia.
In these states, HHC is treated similarly to other hemp-derived cannabinoids, as long as products remain under the 0.3% Delta 9 THC threshold.
States Where HHC Is Likely Legal
Some states have not passed laws specifically addressing HHC but appear to allow its sale under existing hemp laws. These include Kansas, Missouri, New Hampshire, Texas, Wisconsin, Wyoming, and Iowa. For example, Iowa permits hemp-derived cannabinoids but bans smokable hemp products like HHC flower.
States With Restrictions
A handful of states permit HHC but place additional rules on its sale and distribution. California requires strict compliance with hemp regulations, while Connecticut only allows HHC sales through licensed retailers and prohibits online sales. Other states, such as Arizona, Hawaii, Missouri, and Oklahoma, classify HHC as “legal with restrictions,” meaning that products must meet additional compliance or labeling standards.
States Where HHC Is Illegal
HHC is explicitly prohibited in Alaska, Colorado, Delaware, Idaho, Mississippi, Montana, Nevada, New York, North Dakota, Utah, and Washington. These states either classify HHC as a controlled substance or ban hemp-derived intoxicating cannabinoids outright.
States in a Gray Area
In Illinois, Kentucky, Texas, Vermont, and Wisconsin, the legality of HHC is uncertain. Lawmakers in these states are considering new rules that could either clarify or restrict access to intoxicating hemp cannabinoids like HHC.
Quality Control: What to Look for in HHC Products
Because the HHC market is largely unregulated, quality control is critical. Independent analyses of commercial products have shown wide inconsistencies, not only in isomer ratios but also in total cannabinoid content. In some cases, products contained only half of the HHC listed on their labels.
To avoid this, consumers should look for products backed by comprehensive testing. Reputable manufacturers typically follow pharmaceutical-grade protocols, which include:
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Raw material testing before production begins
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In-process testing during manufacturing to ensure consistency
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Final product testing for potency, isomer ratios, and contaminants
Testing should cover residual solvents, heavy metals from catalysts, pesticides from hemp cultivation, microbial contaminants, and mycotoxins that can result from fungal growth.
Another important safeguard is third-party verification.
Certificates of Analysis (COAs) from ISO 17025-accredited laboratories confirm that results are accurate and unbiased. Reliable brands also perform stability testing to ensure their products maintain potency and safety throughout their shelf life.
For consumers, the presence of transparent, publicly available lab reports is the clearest sign of a trustworthy HHC product.
Potential Applications and User Experiences
HHC is still a relatively new cannabinoid, and while formal research is limited, growing user feedback highlights several areas where it may offer unique benefits. Many people describe HHC as producing relaxation without the heavy sedation sometimes linked to traditional THC. This makes it appealing for those who want to ease stress during the day while staying functional.
Daytime Use and Creativity
Users often report that HHC provides a clear-headed sense of euphoria that allows them to remain productive. Some find it useful for creative work, studying, or managing daily responsibilities, since it tends to produce less anxiety and mental fog compared to Delta 9 THC. Our Creativity Blend products contain HHC and other cannabinoids that are perfect on this front.
Stress and Mood Support
Another common theme is improved mood and reduced feelings of stress. While experiences vary, many people say HHC helps them feel calmer and more balanced, which is why it has gained popularity among parents and professionals looking for a functional option.
Physical Comfort and Relaxation
Because HHC interacts with both CB1 and CB2 receptors, some users note effects similar to other cannabinoids known for supporting physical comfort. They describe feeling relief without the impairment that stronger cannabis products can sometimes cause.
Sleep Support
Indica-leaning HHC products are often used in the evening to promote rest. Users frequently share that they fall asleep more easily and experience fewer nighttime awakenings, such as with our Dream Blend Phantom OG Cartridge. The stability of HHC as a compound may also help maintain consistent effects across multiple uses.
Drug Testing: Important Considerations
Drug testing is one of the most common concerns for people considering HHC. While some claims suggest that HHC may not show up, current evidence indicates that it likely can. When your body processes HHC, it produces metabolites that are structurally similar to those from THC, which standard tests are designed to detect.
Most workplace screenings use immunoassay tests that look for THC-COOH metabolites. These tests were created to identify Delta 9 THC use, but they often cross-react with metabolites from other cannabinoids, including HHC. As a result, using HHC may still lead to a positive test result.
The detection window for HHC has not been fully established, but based on what is known about THC, it may remain in the system for several days.
Occasional users could test positive for a couple of days, while regular or heavy users may remain detectable for a week or more.
If drug testing is a concern, it is safest to assume that HHC use could affect the outcome. No hemp-derived cannabinoid product can guarantee a negative result on a standard drug test.
For more information about cannabinoids and drug testing, read our comprehensive guide on what Delta-8 users need to know before drug tests.
Best Practices for HHC Consumption
Getting the most out of HHC while staying safe comes down to dosing, timing, hydration, and environment. Because products can vary widely, being intentional with how you use HHC can make a big difference.
Start Low and Go Slow
This rule applies to all cannabinoids, but it’s especially important with HHC. Beginners should start with a small amount, such as 5-10 mg (about 1-2 vape pulls or a quarter of a gummy), and wait at least 30 minutes before deciding if more is needed. Factors such as body weight, metabolism, tolerance, and desired effects all influence your ideal dose.
Timing and Food Intake
When you consume HHC matters. Morning use on an empty stomach often produces more energetic and mental effects, while evening use after a meal tends to feel more relaxing and body-focused. Because cannabinoids are fat-soluble, eating a meal rich in healthy fats can increase absorption while slowing the onset of effects.
Stay Hydrated
Like other cannabinoids, HHC may cause mild dehydration, leading to dry mouth, red eyes, or headaches. Drinking a glass of water before consuming and keeping water nearby can help minimize these side effects and improve your overall comfort.
Create the Right Environment
Your surroundings can shape your experience as much as the product itself. A calm, familiar space with good ventilation, comfortable seating, and a relaxed atmosphere helps reduce anxiety and supports a positive session. Some people also find that music, lighting, or snacks contribute to a more enjoyable experience.
Consider Cannabinoid Combinations
Pairing HHC with other cannabinoids can change the experience. Our Master Blends collection demonstrates how different cannabinoid combinations create unique experiences. For example, adding CBD may reduce psychoactive intensity while preserving relaxation, CBG can support focus and clarity, and CBN may increase sedation for those who use HHC to support sleep.
Learn more about cannabinoid synergy in our guide to the entourage effect.
Storage and Maintenance Tips
HHC is more stable than many other cannabinoids, but proper storage is still important for preserving potency and safety.
Ideal Storage Conditions
Keep products in a cool, dry place, ideally between 60-70°F, and away from direct sunlight. Extreme heat can thin the oil and damage hardware, while freezing temperatures can make the oil too thick and affect performance. Avoid leaving cartridges in hot cars or cold storage areas for extended periods.
Packaging and Containers
Whenever possible, store HHC products in their original packaging. These are often designed with UV protection and child-resistant features. If you need to transfer products, choose amber or opaque glass containers that limit light exposure. Long-term storage in plastic is not recommended, as cannabinoids can interact with plastic over time.
Cartridges and Disposables
For vape cartridges and disposables, keep them upright to prevent leaks and ensure even oil distribution. If a cartridge clogs, gentle warming with a hair dryer set on low for about 10-15 seconds can usually restore proper airflow.
Our blog post on keeping carts from clogging provides detailed troubleshooting steps.
Making an Informed Choice About HHC
Deciding to try HHC should come from accurate information, realistic expectations, and an understanding of both its potential benefits and limitations.
Many people are drawn to HHC because it offers effects that feel less intense than Delta 9 THC, often with a clearer and more functional headspace. This can make it appealing for stress relief, mood support, or relaxation without feeling overwhelmed.
For those already familiar with cannabis, HHC may provide a similar experience with greater manageability. New users often appreciate its more predictable effects compared to traditional THC products. At the same time, it is important to consider factors such as drug testing and personal comfort with semi-synthetic cannabinoids, as these may influence whether HHC is a good fit for you.
When choosing products, quality should be a top priority. Because HHC products can vary widely, it is best to look for transparent brands that provide detailed lab reports.
Certificates of Analysis should verify cannabinoid content, isomer ratios, and the absence of harmful substances like residual solvents, pesticides, or heavy metals.
Starting with HHC is best approached gradually. Begin with simple, single-cannabinoid products before moving to blends, and keep track of how different doses and formats affect you. Recording details such as onset, peak, and duration will help you fine-tune your experience over time and find the products that work best for your needs.
Browse our complete HHC collection to find the perfect starting point for your exploration.
Why Choose Mellow Fellow for Your HHC Experience
When HHC first appeared on the market, quality was inconsistent. Many products lacked proper testing, contained inactive isomers, or showed traces of unwanted materials. Mellow Fellow set out to change that by adopting pharmaceutical-grade standards from the beginning.
Our team manages the entire process, from sourcing hemp to completing hydrogenation under controlled conditions. Every batch is tested by accredited third-party labs for potency, isomer ratios, residual solvents, pesticides, heavy metals, and microbial contaminants. Results are published openly, giving customers confidence in what they are consuming.
By prioritizing consistency, safety, and transparency, Mellow Fellow has built a reputation as a trusted name in the cannabinoid market - learn more about all of our best HHC vapes right here.
HHC's Place in Your Cannabinoid Wellness Routine
HHC has quickly become one of the most talked-about hemp-derived cannabinoids, offering a middle ground between the intensity of Delta 9 and the mellowness of Delta 8. Its stability, functional effects, and growing range of product options make it appealing for both new and experienced users.
Still, the experience can vary greatly depending on isomer ratios and product quality, making transparency and third-party testing essential. Legal status remains mixed across states, and drug tests may still detect its metabolites.
With careful dosing, proper storage, and informed product choices, HHC can be a practical addition to a cannabinoid wellness routine for those seeking balanced effects.
Ready to explore HHC? Browse our complete HHC collection to discover premium products backed by science and crafted for consistency.
For those new to alternative cannabinoids, our beginner's guide to Delta 9 gummies provides foundational knowledge about cannabinoid consumption. And if you're interested in the broader spectrum of hemp-derived compounds, don't miss our guide to alternatives to THC you haven't heard of.
Frequently Asked Questions
Does HHC Build Tolerance Like THC?
Early reports suggest that HHC may build tolerance more slowly than Delta 9 THC. Some users say they can use it daily without needing to increase their dose as often. However, scientific studies are still limited, and individual tolerance can vary based on metabolism, frequency of use, and dosage.
How Long Does HHC Stay in Your System?
The exact detection window for HHC is not fully established. Based on similarities to THC, occasional users may test positive for a few days, while frequent users could remain detectable for a week or longer. Heavy daily use could potentially extend that window to several weeks.
Why Is HHC More Stable Than THC?
HHC is created through hydrogenation, which removes double bonds from the THC structure. This makes the molecule more resistant to oxidation and degradation. As a result, HHC products often maintain potency for longer periods compared to Delta 9 or CBD under similar storage conditions.
Can HHC Be Combined With Other Cannabinoids?
Yes, many consumers combine HHC with cannabinoids like CBD, CBG, or CBN to modify the effects. CBD may help reduce intensity, CBG can promote clarity and focus, and CBN is often used to support relaxation and sleep. This type of combination is sometimes referred to as the entourage effect.
Is HHC Safer Than Other THC Variants?
Current preclinical research suggests HHC does not pose significant concerns for heart or liver safety at typical use levels. However, some cytotoxicity was observed in lung cells at very high concentrations. More research is needed, and users should rely on products tested for purity and contaminants.
Where Is HHC Legal in the United States?
HHC is federally legal under the 2018 Farm Bill if derived from hemp and containing less than 0.3 percent Delta 9 THC. State laws vary: it is legal in states like Florida, Georgia, and Indiana, restricted in others like Connecticut and Arizona, and banned in places such as New York, Nevada, and Washington.
Sources
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Studies Pertaining to the Emerging Cannabinoid Hexahydrocannabinol (HHC) | ACS Chemical Biology
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Hexahydrocannabinol and closely related semi-synthetic cannabinoids: A comprehensive review - PubMed
FDA DISCLAIMER: The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from healthcare practitioners.
WARNING: Keep out of reach of children and pets. Must be 21 years or older to purchase. Do not use if pregnant, nursing, or planning to become pregnant. Use of this product can result in failing a drug test for marijuana. Do not drive or operate machinery. Products contain less than 0.3% Δ9-THC in compliance with the 2018 Farm Bill.
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Very informative and well-written!
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