Best Strains for Entourage Effect

Nov 9, 2023

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For as long as cannabis has been a mainstream part of society, it’s been known that the effects extend beyond a simple THC percentage. The wide variety of experiences, which can have one person feeling relaxed and mellow and another creative and energized, could be attributed to what we know as “the entourage effect.”

The entourage effect is an exciting idea, piquing the interests of users and scientists alike since the term was first coined by renowned cannabis scientist Dr. Raphael Mchoulam back in 1999. 

While over two decades have passed, we’re still discovering how the entourage effect might open up new avenues for possible therapeutic benefits and more integral cannabis experiences. 

One thing we know is that some strains might be doing a better job and bringing the entourage effect to life than others. The synergy between cannabinoids and terpenes brings on a spectrum of effects, so today, let’s explore the why and how of the entourage effect.

Key Takeaways

  • The entourage effect is when cannabinoids and terpenes work together to provide specific effects or experiences. 
  • Strains with a balanced composition of different cannabinoids and terpenes are best for the entourage effect. 
  • Bubba Kush, Green Crack, and Jungle Cake are good entourage effect strains. 

What is the Entourage Effect?

Curious about what the entourage effect is? Let’s exemplify it with a banana sundae: cocoa, sugar, vanilla, milk, and strawberries, all these ingredients are necessary to get the full flavor of a banana sundae in every spoonful. 

The entourage effect is the synergy between all of the ingredients - and how they play off each other to create a unique experience. 

Cannabis is not unlike a banana sundae. It’s filled with THC, CBD, CBG, HHC, Delta 10, Delta 8, and any other cannabinoid you can think of. It’s also packed with terpenes like limonene, myrcene, and caryophyllene, to name just a few. 

If you want to experience just THC, it’s like having just vanilla ice cream. Find a strain with a unique blend of terpenes and cannabinoids that work together, and your experience is an ice cream sundae.

The entourage effect, simply said, is the orchestration of compounds that go beyond the usual focus on THC, acknowledging the range of experiences that the collective influence of cannabinoids and terpenes can access. 

So, how can you tap into the entourage effect?

When it comes to the entourage effect, not all strains are created equal. With each one unique in its structure of cannabinoids and terpenes, user experience can vary from indicas, sativas, and hybrids. 

This fact is exciting because it means that it’s possible to personalize your cannabis experience and tap into the entourage effect by picking strains with unique profiles. 

Now, choosing a strain can be empowering (and even an art form). By knowing the basics about terpenes and cannabinoids and looking for strains that suit your preferences and needs, you’re able to tailor the experience. 

For medical users, this shines a light on using cannabis for specific needs like pain relief, mood enhancement, or creative inspiration.

How Does the Entourage Effect Work?

In order to understand the cannabinoids and terpenes that ultimately define your cannabis experience, here’s a little breakdown of the most common and well-known compounds and flavonoids you’ll find: 


Cannabinoids are chemical compounds in the cannabis plant that interact with the body’s endocannabinoid system, affecting physiological processes and providing unique effects.

  • THC: There’s a reason why THC is the rockstar of the cannabis world. This compound is highly psychoactive and can cause you to feel euphoric, giggly, and relaxed. 
  • CBD: This compound is similar to THC, but it has no psychoactive effects. The effects of CBD tend to be calming and relaxing. 
  • Delta 8: Another chemical cousin of THC, Delta 8 is a psychoactive cannabinoid that has similar yet less intense effects than THC. 
  • CBG: Known as “the mother of all cannabinoids,” CBG is a non-psychoactive cannabinoid with potential benefits. 
  • CBN: Used in therapeutic and holistic settings, CBN may provide therapeutic benefits without psychoactive effects. 
Best Strains for Entourage Effect


Terpenes are aromatic compounds, meaning they contribute to the flavor and scent of cannabis strains. However, they also work alongside cannabinoids to produce a wide range of effects, opening up the door to potential therapeutic use.

  • Myrcene: Known for calming and sedative effects. 
  • Pinene: Good for alertness and mental clarity. 
  • Linalool: Popular terpene for mood management. 
  • Caryophyllene: Great for mood elevation. 

Ratio for Overall Experience

There are over 100 cannabinoids and 200 terpenes that can be found in cannabis, so it comes as no surprise that there are more than 700 unique strains in the world. 

Mixing and matching these can turn the dial on the overall experience: for example, a strain with high CBD and myrcene is perfect for settling down after a long day. 

On the other hand, a strain high in THC and pinene might make you feel alert and invigorated. 

Understanding the dynamics of different blends of terpenes and cannabinoids can turn you from a casual user into a cannsseur, able to choose strains that carry specific qualities you desire, whether you’re looking to expand your creativity, wallow in relaxation, feel energized, or treat specific needs.

Best Strains for the Entourage Effect 

It’s no use to talk about the entourage effect without offering you a taste of this unique experience. Here are our favorite Mellow Fellow strains that’ll help you tap into the entourage effect: 

Green Crack

Green Crack is a great choice if you want an entourage effect that’s synonymous with a burst of energy. This sativa strain boasts a blend of cannabinoids like HHC and CBG, and terpenes like myrcene and pinene enhance the mood-lifting effects of this electrifying and potent strain. Try it out with our Picasso Euphoria Blend Green Crack Disposable.

“This right here is my favorite. It makes me goofy, like back in the day you know what I mean? I won’t realize it at first and then I’ll be like huh, I am in rare form tonight aren’t I? Ohhh right it’s the green crack. Highly recommend especially if you like to entertain your friends.”

- Elizabeth

Bubba Kush

If you want a more serene experience, an indica-dominant strain like Bubba Kush might be just what you’re looking for. Filled with HHC, CBD, and other unique cannabinoids, our Vape Cart Duo includes a cartridge filled with this unique linalool- and myrcene-packed strain. This one is sure to elevate your relaxation.

“I honestly think this is the best blend so far! Indica and hybrid. Strongest HHC content and love the Bubba Kush.”

- Katie

Starberries N Cream

Looking for a balance between invigorating and relaxing? A hybrid like the creamy and cozy Starberries N Cream Dream Blend Cereal Bar promises a harmonious blend of relaxation and euphoria, thanks to a unique cannabinoid blend and terpenes like limonene and caryophyllene that’ll have you feeling clear-headed yet mellow.

“Take small bites. It’s my favorite blend it’s amazing."


- Jill

Jungle Cake

If you’re curious about exploring the exotic strains, check out Jungle Cake. This hybrid stabilizes the effects of HHC, Delta 8, PHC, CBD, and CBG, offering an extremely well-balanced experience that’s both calming and energizing. With pinene and terpinolene making for an earthy flavor, the effects will have your feet on the ground while letting your mind explore. Try out our Jungle Cake Recover Blend Disposable.

“Enjoying this 2ml vape. Nice mellow relaxing feeling....nothing intense here.. just chill recovery time. Solid vape design. Great site prices.”

- Jamie

OG Kush

The classics are classic for a reason, which is why OG Kush will always be a fan favorite. This celebrated hybrid strain features a balanced blend of cannabinoids that both energize and mellow out, making for a familiar cannabis experience. 

With myrcene and limonene taking over the flavor profile and mood-enhancing effects, Our O’Keeffe’s Tranquility Blend might just be the best way to explore the entourage effect.

“This has definitely been fantastic and has done so well to help unwind me from my work days and to release my anxiety while toning down my depression to a nearly unnoticeable factor. I will be buying these again.”

- EJ

Final Thoughts

The entourage effect makes one thing very clear: cannabis can be experienced across a spectrum. In the kaleidoscope of possibilities, the entourage effect is the artist that decides which color gets placed where. 

Understanding the basics of cannabinoids and terpenes won’t just make you a cannabis expert - it’ll empower you to be able to tailor your cannabic experiences. 

Picking the right strain is the most important aspect of the entourage effect, and this decision can ultimately only be made by you since you know what your needs and preferences are. Exploring different strains and cannabinoids can be a valuable experience that leaves you in control of the experiences you have. 

The key lies in exploration: encourage yourself to step out of your comfort strains, research about different effects and benefits, and don’t be afraid to try something new. Paying attention to the interplay of cannabinoids and discovering the strains that work for you are all a part of the adventure. 

Best Entourage Effect Strain: Frequently Asked Questions

What is the Significance of the Entourage Effect when Choosing a Cannabis Strain?

The entourage effect can be useful as different synergies between distinct cannabinoids and terpenes can highlight different effects and experiences. 

What are Some Reputable Sources to Find the Best Entourage Effect Strains?

Reputable brands that are transparent and follow safety guidelines, like Mellow Fellow, are the best places to buy entourage effect strains. 

How Can I Identify a Strain That Will Provide a Pronounced Entourage Effect?

Identify strains with a pronounced entourage effect by paying attention to a balanced combination of varying cannabinoids and terpenes. 

Can the Entourage Effect Help in Alleviating Specific Symptoms or Conditions?

The entourage effect may facilitate therapeutic applications by being able to tailor specific effects and benefits with certain cannabinoid and terpene blends. However, more research is needed before we can claim that the entourage effect does alleviate a condition.

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