THCb vs. Delta 8: The Full Cannabinoid Comparison
When it comes to cannabinoids, the spotlight often falls on THC and CBD. But there’s much more out there. Today, we want to introduce you to two lesser-known compounds that are piquing the curiosity of cannabis enthusiasts. We’re talking about THCb and Delta 8 THC.
While both offer unique effects and potential benefits, the subtle distinctions between them make each one special.
Today, we’re going to examine both cannabinoids in great detail to learn what they are, how they might affect you, their therapeutic potential, and what makes them different.
By the end of this THCb vs Delta 8 comparison, you’ll have all the information you need to make an informed decision, so keep reading!
Key Takeaways
- THCb is a novel cannabinoid similar to THC but with a unique butyl side chain that may increase its potency compared to Delta 9 THC.
- Delta 8 THC is a milder, less potent alternative to Delta 9 THC, offering a more relaxed, clear-headed experience ideal for those sensitive to intense highs.
- THCb may offer stronger effects and could potentially be more effective for pain relief, while Delta 8 is better known for reducing anxiety and promoting relaxation.
- Both cannabinoids show potential benefits, including pain relief, mood regulation, and appetite stimulation, but THCb is generally more potent and stimulating.
What is THCb?
THCb, or tetrahydrocannabutol, is a novel cannabinoid recently discovered. The Discovery of THCb - PubMed revealed a compound similar to THC but with some key differences.
THCb has a butyl side chain instead of a pentyl side chain like Delta 9 THC, which may significantly increase its potency compared to Delta 9.
This structural difference may allow THCb to bind more strongly to cannabinoid receptors in the brain, particularly the CB1 receptors, potentially producing a more cerebral feeling.
Although some sources indicate that THCb may have a potency comparable to THCp, which would make it over 30 times more potent than Delta 9 THC, this has not been confirmed, and more research is needed.
Furthermore, anecdotal evidence indicates that although THCb may have a higher binding affinity than Delta 9 THC, the effects are much the same, and more cerebral than Delta 9.
Let’s move on and discuss how THCb is made.
How is THCb Made?
While THCb occurs naturally in cannabis plants, it’s only present in trace amounts. This scarcity makes natural extraction impractical for commercial production, as it would require far too much plant matter.
Because of this, most commercial THCb is synthesized from hemp-derived CBD through a chemical process called isomerization. This process involves altering the molecular structure of CBD to create THCb, allowing for larger-scale production of this potent cannabinoid.
What are the Effects of THCb?
Although there is far more research required on THCb, anecdotal reports indicate that THCb is quite cerebrally stimulating and may produce a more creative, energizing, and uplifting effect than the more sedative Delta 9 THC.
THCb may also produce feelings of calmness and relaxation. This cannabinoid is also thought to produce a euphoric effect similar to or possibly stronger than Delta 9 THC.
What is Delta 8 THC?
Delta 8 is a cannabinoid similar to its more famous cousin, Delta 9 THC. As an isomer of THC, Delta 8 has the same chemical formula but a slightly different atomic arrangement.
The key difference lies in the position of a double bond. Delta 8 has this bond on the 8th carbon chain, while Delta 9 THC has it on the 9th.
According to current research, this difference in chemical structure means that Delta 8 has a weaker binding affinity with CB1 receptors than Delta 9, potentially making it less potent and psychoactive. We’ll discuss this in greater detail below.
How is Delta 8 THC Made?
Just like with THCb, although Delta 8 occurs naturally in hemp plants, only in trace amounts. Therefore, most Delta 8 products you can buy are made by converting CBD through isomerization. It’s the same production principle as with THCb, but with slightly different elements, therefore producing a different cannabinoid.
What are the Effects of Delta 8?
When you consume Delta 8, you can expect a milder experience compared to traditional Delta 9 THC. Research indicates that users often report feeling relaxed and clear-headed, with reduced anxiety levels. Many describe the effects as a middle ground between CBD and Delta 9 THC.
While Delta 8 is still psychoactive, the relaxation, euphoria, sedation, and overall cerebral “high” often associated with Delta 9 are generally less pronounced.
This gentler high makes Delta 8 an appealing option for those who find Delta 9 THC too intense or anxiety-inducing. You might appreciate Delta 8 if you're looking for a more subtle, functional experience that allows you to remain productive and focused.
Something that everyone always wants to know is how potent a cannabinoid is, particularly in comparison to Delta 9 THC, so let’s take a look at just how strong THCb and Delta 8 THC are.
THCb vs. Delta 8: Potency Comparison
To make things simple, when comparing the potencies of THCb and Delta 8 THC, we’ll use Delta 9 THC as a baseline, as this is likely what most people are familiar with.
Let’s compare THCb and Delta 8 based on their potency.
THCb Potency
In terms of THCb, some assert that it may be up to 30 times more potent than Delta 9 THC, which would make it one of the strongest cannabinoids in existence.
However, other sources indicate that although it may have a slightly higher binding affinity with CB1 receptors than Delta 9 THC, its overall potency and effects are likely similar.
According to anecdotal evidence, THCb is more cerebrally stimulating and uplifting than Delta 9 THC, and possibly slightly more intoxicating, although not by much. One way or another, further research is required.
However, it’s safe to say that THCb is no weaker than Delta 9, which means that beginners should exercise a bit of caution with it, as it has the potential to be quite intoxicating.
Delta 8 Potency
According to modern research, Delta 8 has a lower binding affinity with CB1 receptors than Delta 9 THC, meaning it has less psychoactive potential.
According to current research, Delta 8 THC is anywhere from half as potent to two-thirds as potent as Delta 9 THC, meaning that it is quite likely also less potent than THCb, although exactly how much remains somewhat of a mystery.
Delta 8's milder potency makes it more approachable for newcomers or those sensitive to THC's effects. You might find Delta 8 provides a gentler, more manageable high that allows you to remain functional throughout the day.
This characteristic has made Delta 8 popular among users looking for a middle ground between CBD and traditional THC.
Potency aside, let’s move on and determine what the potential benefits of both THCb and Delta 8 are.
Potential Benefits of THCb vs. Delta 8
When comparing THCb and Delta 8, you'll find differences in their potential benefits, although there are also some great similarities.
Among other potential benefits, THCb and Delta 8 may both be able to relieve pain, improve mood and mental state, and stimulate appetite. Understanding these can help you choose the right cannabinoid for your needs.
Here is a comparison of the biggest potential benefits of THCb and Delta 8 THC:
Pain Relief
Both THCb and Delta 8 show promise for pain relief, but THCb's possible higher potency may offer more significant effects. You might find THCb particularly useful for chronic or severe pain conditions.
Current research in mice shows that THCb may have anti-inflammatory and analgesic
properties, meaning it may relieve pain and inflammation.
Delta 8, while less potent, still provides potential pain-relieving properties, as displayed by current studies. Its milder nature makes it suitable for managing everyday aches and pains without overwhelming psychoactive effects.
However, there are case studies that indicate that many who suffer from painful conditions and those characterized by inflammation report that Delta 8 is effective at relieving symptoms. Whether THCb is more effective at pain relief requires further research.
Possible Anxiety Reduction and Mood Regulation
Delta 8 often stands out for its potential anxiety-reducing properties. Many users report feeling calm and clear-headed after consuming Delta 8, making it a popular choice for those dealing with anxiety symptoms.
Here is a study that shows that as many as 51% of those who consume Delta 8 do so for its therapeutic potential, particularly its ability to manage symptoms related to anxiety.
THCb's intense potency may not be ideal for anxiety management. Some users find its strong effects can increase anxiety or paranoia, especially in higher doses. If you're sensitive to THC or prone to anxiety, Delta 8 might be the safer choice.
However, for those who are not overly sensitive to the effects of cannabinoids, the potential of THCb to uplift, energize, and produce a sense of euphoria may be beneficial in terms of regulating mood and managing symptoms of anxiety. It’s difficult to tell unless you try it for yourself.
Appetite Stimulation
Both cannabinoids may effectively stimulate appetite, which is beneficial for individuals with various issues that result in no or limited appetite.
THCb's potency may translate to stronger hunger cravings. This intense appetite stimulation could be particularly helpful for those struggling with severe appetite loss.
Although not much research has been performed on THCb’s potential for appetite stimulation, its similarity to Delta 9 THC could mean that it has that same potential, as Delta 9 is known for stimulating appetite.
Delta 8 offers a more moderate increase in appetite. It might be useful for gentle appetite enhancement without the risk of overeating. Studies have shown that Delta 8 produces a moderate increase in appetite and food consumption, although how this compares to THCb is yet to be seen.
Acting as a Sleep Aid
Although more research is needed on both fronts, THCb and Delta 8 may help you sleep better. Delta 8, although not as strong as Delta 9, is thought to share many of the same sedating properties. It likely won’t produce the same couch-lock as Delta 9, but it will likely help relieve pain, regulate your mood, and relax you.
As far as THCb for sleep is concerned, the results are mixed. Some may find that THCb is uplifting and energizing initially, which would mean that it’s not the best choice for sleep, at least not if you want to sleep right away.
That said, some also find that its sedative properties kick in a few hours after consumption, almost like a burnout. At any rate, Delta 8 is likely the better option for sleep.
Is THCb or Delta 8 Better for Daytime Use?
Delta 8 is likely the better option for daytime use. However, there are some nuances to consider.
Delta 8, as mentioned above, can be slightly sedating, although the “high” itself is not very potent. On the other hand, THCb is known for being more uplifting and cerebrally stimulating, but also more intoxicating, with a higher possibility of impairing your cognition to a higher degree.
As you can see, there is a tradeoff to consider here. That aside, let’s find out what the potential side effects of both THCv and Delta 8 might be.
What Are the Side Effects of THCb and Delta 8?
When experimenting with THCb and Delta 8, you should be aware of potential side effects. Both cannabinoids can cause dry mouth, red eyes, increased heart rate, and coordination issues. However, THCb's higher potency means these effects may be more pronounced.
If you're prone to anxiety or have a low tolerance, THCb requires extra caution. Its potential for intense effects can trigger anxiety or paranoia, especially in higher doses. The Durban Poison Delta 8 THC Premium Disposable Vape offers a milder alternative, allowing you to experience cannabinoid effects with potentially fewer side effects.
For both THCb and Delta 8, start with a low dose and gradually increase to find your optimal level. This approach minimizes the risk of negative side effects while allowing you to gauge your personal tolerance. Remember, individual reactions can vary, so pay attention to how your body responds to each cannabinoid.
Best THCb Products on the Market
While THCb is a relatively rare cannabinoid, it is possible to find it if you know where to look, such as at Mellow Fellow. Although THCb may not be available in many forms right now, vaping is certainly an option.
Here are some great THCb vapes to try:
Introvert NYC Gas Mask Vape
The Introvert NYC Gas Mask Vape by Mellow Fellow combines THCb with other cannabinoids like Delta 8, THCp, HHC, CBG, and CBN in a potent live resin blend. This is an indica, so it is likely to be somewhat sedating.
This 1ml disposable vape delivers the earthy, citrus-fuel flavor profile of the Gas Mask strain, enhanced with hints of sour cherry. Made for relaxation, it provides a calming and introspective experience, ideal for winding down or finding focus.
Introvert Blend Blueberry OG Vape
The Introvert Blend Blueberry OG Vape offers a unique combination of THCb, Delta 8, HHC, and CBN, delivering a balanced, relaxing experience.
This 4ml live resin disposable vape is infused with the classic Blueberry OG strain, known for its sweet, berry-forward flavor with subtle earthy undertones. Ideal for evening use, it’s designed to help you unwind, promoting both mental relaxation and physical comfort.
Best Delta 8 Products on the Market
Delta 8 is far more common and readily available. You can find it in vapes, edibles, and more. Mellow Fellow happens to have a huge selection of Delta 8 products, with the following being two of the most popular.
Here are some great Delta 8 products for you to check out:
Mellow Fellow’s Euphoria Blend Green Crack Live Resin Disposable Vape
Mellow Fellow’s Euphoria Blend Green Crack Live Resin Disposable Vape combines THCb, Delta 8, HHC, THCp, and CBD for an energizing, mood-boosting experience. Infused with the Green Crack strain, this 2ml vape offers bold, fruity flavors with hints of citrus and earthy undertones, perfect for daytime use.
Made for those looking to uplift their spirits and stay productive, this blend delivers a smooth, flavorful draw while providing the powerful combination of multiple cannabinoids, providing users a stimulating, euphoric high.
Dream Blend Fruit Punch M-Fusion Gummies
The Dream Blend Fruit Punch M-Fusion Gummies offer a delicious, tropical flavor infused with Delta 8 with several other cannabinoids for a total of 1000mg per pack. These fruit-flavored edibles are designed to provide a balanced and relaxing experience, making them ideal for unwinding at the end of the day.
The combination of cannabinoids creates a calming, mildly euphoric high, enhanced by the vibrant taste of fruit punch. Enjoy a convenient, flavorful way to experience the unique effects of multiple cannabinoids.
Is THCb or Delta 8 Right for You?
Both THCb and Delta 8 THC offer unique experiences and potential benefits, each suited to different needs and preferences. THCb is a potent cannabinoid that may provide a more cerebral and intense high, potentially making it a good option for those seeking stronger effects for pain relief and mood enhancement.
Delta 8 THC, on the other hand, offers a milder and more manageable experience, often preferred by those looking for relaxation and relief without the intensity of Delta 9 THC.
It also has a gentler effect on anxiety, making it ideal for daytime use. As research continues, both cannabinoids may offer new therapeutic options for various needs, so consider your personal tolerance and desired effects when choosing between them.
Whether THCb, Delta 8, or anything in between, Mellow Fellow is always the place to be!
Frequently Asked Questions
What Makes THCb More Potent Than Delta 8 THC?
THCb has a unique molecular structure with a butyl side chain, which may allow it to bind more effectively to CB1 receptors in the brain. This could increase its potency and provide a more cerebral experience than Delta 8 THC.
Is Delta 8 Better Than THCb for Daytime Use?
Delta 8 THC is typically milder and more balanced, making it better suited for daytime use. It can provide relaxation without significantly impairing cognition, while THCb is more intense and potentially more intoxicating.
How Are THCb and Delta 8 Produced?
Both THCb and Delta 8 occur in small amounts in cannabis plants. For commercial use, they are typically synthesized from CBD through a process called isomerization, allowing for a more practical production scale.
Sources
- Endocannabinoid Binding to the Cannabinoid Receptors: What Is Known and What Remains Unknown - PMC (nih.gov)
- THC-B Cannabinoid | Arvida Labs
- Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol | Journal of Natural Products (acs.org)
- A novel phytocannabinoid isolated from Cannabis sativa L. with an in vivo cannabimimetic activity higher than Δ9-tetrahydrocannabinol: Δ9-Tetrahydrocannabiphorol - PMC (nih.gov)
- 5 Things to Know About Delta-8 Tetrahydrocannabinol: Delta-8 THC - PMC (nih.gov)
- https://cannabisresearch.mcmaster.ca/what-is-delta-8-tetrahydrocannabinol-delta-8-thc/
- Chemistry and Pharmacology of Delta-8-Tetrahydrocannabinol - PMC (nih.gov)
- Study: Users say delta-8-THC is delta-9’s ‘nicer younger sibling’ - University at Buffalo
- Phytocannabinoid Pharmacology: Medicinal Properties of Cannabis sativa Constituents Aside from the “Big Two” (coloradochromatography.com)
- Review of delta‐8‐tetrahydrocannabinol (Δ8‐THC): Comparative pharmacology with Δ9‐THC - Tagen - 2022 - British Journal of Pharmacology - Wiley Online Library
- Marijuana and Body Weight - PMC (nih.gov)
- Very low doses of delta 8-THC increase food consumption and alter neurotransmitter levels following weight loss - PubMed (nih.gov)
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