What are the Benefits of CBG?

Jun 30, 2022
What are the Benefits of CBG? - Mellow Fellow

Cannabinoids have taken the wellness community by storm, with CBD and THC being at the forefront. But there's a new cannabinoid in the industry making big waves due to its great therapeutic potential: CBG.

Known as the “mother of cannabinoids”, CBG is the precursor to CBD, THC, and CBC, among many other important compounds in the cannabis plant. Without CBG, we wouldn’t have any of the other cannabinoids that we all know and love. 

CBG shows many potential benefits for both the mind and body, including relief from pain and inflammation, anti-stress, and increased energy and focus, all of which we’ll discuss below.

At Mellow Fellow, we aim to provide safe, pure, and effective CBG products. We provide up-to-date certificates with every batch of CBG products we produce.

So, what exactly is CBG, its possible therapeutic applications, and how does it differ from its more famous counterparts? What are the benefits of CBG? Keep reading to find out. 

Key Takeaways 

  • CBG, known as the "mother of cannabinoids," plays a crucial role in the formation of other cannabinoids like CBD and THC, offering unique therapeutic benefits.
  • CBG interacts directly with CB1 and CB2 receptors, providing distinct effects compared to CBD, such as appetite stimulation, antibacterial properties, and neuroprotection.
  • The top potential benefits of CBG include anti-inflammatory effects, neuroprotective properties, antibacterial activity, appetite stimulation, and mood support.
  • Incorporating high-quality CBG products into your wellness routine can help manage inflammation, support brain health, enhance mood, and provide other therapeutic benefits.
  • Various CBG products, such as edibles, tinctures, and topicals, offer diverse ways to incorporate this cannabinoid into your wellness routine.

Let’s start by finding out what exactly CBG is. 

 

What Is CBG?

CBG, or cannabigerol, is a non-psychoactive cannabinoid found in hemp plants. It's often referred to as the "mother of all cannabinoids" because other cannabinoids, such as CBD and THC, are derived from cannabigerolic acid (CBGA), the acidic form of CBG.

As the hemp plant matures, enzymes convert CBGA into other cannabinoids. This means that CBG is usually present in low levels in mature plants, typically less than 1% by weight.

Like other cannabinoids, CBG interacts with the body's endocannabinoid system, a complex network of receptors and neurotransmitters that helps regulate various physiological processes, such as mood, appetite, sleep, and immune function.

Although CBG is one of the many cannabinoids found in cannabis plants, it differs significantly from the others that you might be familiar with, such as CBD and THC. Let’s find out what makes them different. 

How CBG Differs from CBD and THC

While CBD and THC are the most well-known cannabinoids, CBG has some distinct differences, especially when compared to THC and CBD. Let’s start by comparing CBG to THC.

CBG vs. THC

Unlike THC, CBG is non-psychoactive, meaning it won't produce the "high" associated with cannabis use, particularly with various forms of THC, whether Delta 8, 9, 10, or Delta 11 THC. It’s the difference in chemical or molecular structure that is thought to account for the lack of psychoactivity when compared to THC. 

Although, a lack of psychoactivity does not mean that CBG does not have great therapeutic potential. 

It’s this exact lack of a “high” that makes it so useful, as it may be able to treat a variety of conditions and symptoms while not being intoxicating. This is something that those who use cannabis for therapeutic purposes should appreciate. Speaking of non-psychoactive cannabinoids, let’s compare CBG and CBD.

CBG vs CBD

CBG also interacts with the body's cannabinoid receptors differently than other cannabinoids, such as CBD. 

According to a cannabigerol overview study from ScienceDirect, CBG binds directly to both CB1 and CB2 receptors. At the same time, CBD has little affinity for these receptors and works indirectly by modulating other receptors and signaling pathways.

This difference in receptor interaction may explain why CBG has shown potential for different therapeutic applications than CBD, such as appetite stimulation, antibacterial activity, and neuroprotection, while also having a distinct lack of a noticeable “high” or psychoactive effect. 

An interesting note is that although both cannabinoids interact differently with the body, CBG and CBD do not produce a noticeable “high” while also both having their distinct therapeutic potential. 

Since we’re talking about endocannabinoid receptors, it makes sense to discuss how CBG works in the human body. 

How Does CBG Work in the Body?

CBG interacts with the body's endocannabinoid system (ECS), a complex network of receptors, enzymes, and endocannabinoids that help regulate various physiological processes. The two main types of cannabinoid receptors in the ECS are CB1 and CB2.

CBG binds to both CB1 and CB2 receptors, which are found throughout the body. CB1 receptors are primarily located in the central nervous system, while CB2 receptors are more abundant in the immune system and peripheral tissues.

When CBG binds to these receptors, it can influence specific physiological systems and help address various health issues. 

For example, CBG's interaction with CB1 receptors in the brain may help regulate mood, appetite, and sleep, while its binding to CB2 receptors in the immune system may contribute to its anti-inflammatory and pain-relieving potential.

Let’s look more in-depth at how CBG interacts with the body’s ECS. 

CBG’s Influence on the Endocannabinoid System

A cannabinoids and receptor interaction study sheds light on how CBG interacts with the ECS. The study found that CBG acts as a partial agonist of both CB1 and CB2 receptors, meaning it can activate these receptors but with less potency than a full agonist like THC.

This partial agonist activity may explain why CBG has shown potential for various therapeutic applications without the psychoactive effects associated with THC. Additionally, CBG may help enhance the effects of other cannabinoids, such as CBD, through a phenomenon known as the entourage effect, although more research is required on this front.

The entourage effect suggests that the combined action of multiple cannabinoids and terpenes in hemp plants may produce more significant therapeutic benefits than any single compound alone. By working synergistically with other cannabinoids, CBG may contribute to the overall effectiveness of hemp-derived products in promoting health and well-being.

With the basics of CBG covered, let’s find out its top potential benefits. 

Top 5 Potential Benefits of CBG

Now that you understand how CBG works in the body, let's explore some of its most promising potential benefits, such as fighting inflammation, protecting your brain, regulating mood, and more.

Here are the potential benefits that CBG brings to the table: 

1. Potent Anti-inflammatory Potential

CBG has shown remarkable anti-inflammatory effects, making it a strong contender for the best cannabinoid for inflammation and pain relief . A Cannabinoids and Pain Modulation study from NIH highlights CBG's potential to reduce inflammation by interacting with the body's endocannabinoid system and modulating the immune response. Simply put, CBG can inhibit the activation of pro-inflammatory cells

This potential anti-inflammatory action may help alleviate symptoms of various conditions related to both acute and chronic inflammation. CBG may also contribute to pain relief by reducing inflammation, making it a promising natural alternative to traditional pain medications. Aside from its anti-inflammatory potential, CBG also shows promise as a neuroprotectant. 

2. Neuroprotection 

CBG has demonstrated neuroprotective properties, which means it may help protect brain cells from damage caused by inflammation and oxidative stress. This protective effect is particularly relevant for various neurodegenerative disorders that can lead to neurological degradation.

Research suggests that CBG may reduce neuroinflammation and oxidative stress, two key factors contributing to the progression of these disorders. By safeguarding neurons from damage and promoting their survival, CBG may offer hope for slowing down or preventing the development of these debilitating neurological conditions. 

3. Antibacterial Activity

One of the most exciting potential benefits of CBG is its antibacterial activity, particularly against drug-resistant strains of bacteria. As antibiotic resistance becomes an increasing global health threat, the search for new antimicrobial agents is more critical than ever.

Studies have shown that CBG may be effective against methicillin-resistant Staphylococcus aureus (MRSA). This dangerous bacterium can cause severe infections and is notoriously difficult to treat with conventional antibiotics. 

CBG's ability to combat these resistant bacteria highlights its potential as a novel therapeutic agent in the fight against antibiotic resistance.

4. Appetite Stimulation

CBG may also help stimulate appetite, which can be beneficial for individuals struggling with appetite loss due to various medical conditions or treatments. 

Unlike THC, which is known for its appetite-stimulating effects but also produces intoxicating effects, CBG offers a non-psychoactive alternative.

Research suggests that CBG may increase appetite by interacting with the body's endocannabinoid system, specifically the CB1 receptors in the brain that regulate hunger and satiety. 

This appetite-stimulating effect could improve the quality of life for those dealing with unintended weight loss and malnutrition.

5. Potential Mood Benefits

Finally, CBG may offer potential mood benefits by interacting with serotonin receptors involved in mood regulation. Serotonin is a neurotransmitter that plays a crucial role in emotional well-being, and imbalances in serotonin levels have been linked to various mood disorders, such as depression and anxiety.

CBG has shown an affinity for the 5-HT1A serotonin receptor, which is a target for many antidepressant and anti-anxiety medications. By modulating the activity of this receptor, CBG may help promote a more balanced and positive mood, potentially offering a natural approach to managing emotional health. 

Studies show that when compared to a placebo, CBG demonstrates great anti-anxiety potential in humans. 

 

How to Incorporate CBG Into Your Wellness Routine

Incorporating CBG into your wellness routine can be done in many ways, including smoking CBG-infused flower, vaping CBG concentrate, eating CBG edibles, using tinctures, and roll-on topicals.

Let’s see what each of these CBG consumption methods has in store for you:

Smoking CBG-Infused Flower

Smoking CBG-infused flower is a classic and straightforward way to enjoy CBG. You’ll feel the effects almost instantly, usually within minutes, which makes it great for when you want a quick mood boost or to wind down. 

The effects last about one to three hours, so it’s perfect for short-term relief or relaxation. If you enjoy the ritual of smoking, this could be your go-to. 

However, smoking might not be the best choice if you have sensitive lungs or prefer to keep things discreet. Smoking can be harsh and less portable compared to other methods.

Vaping CBG Concentrate

Vaping CBG is like a cleaner, smoother version of smoking. It still gives you those quick effects, usually within five to ten minutes, but without the harshness of smoke. Depending on your body and how much you use, the effects can stick around for one to four hours. 

Vaping is awesome if you need something fast-acting but want to avoid the smoke. Plus, it’s super easy to take with you and way more discreet than lighting up a joint. 

Just ensure you’re using quality CBG concentrate and keep your device clean to avoid unwanted extras. If you’re not a fan of inhaling, this might not be your best bet.

Eating a CBG Edible

Edibles, like CBG gummies or snacks, are a tasty, easy way to add CBG to your day. They take a bit longer to kick in, usually anywhere from 30 minutes to a couple of hours, but the effects last a good while, sometimes up to eight hours or more. 


This is a great option if you want a slow, steady effect that lasts through the day. Edibles are perfect for anyone who prefers not to smoke or vape, and they’re super discreet.

Just remember, because they take a while to work, they’re not ideal if you’re looking for immediate results. Start with a low dose to see how it feels, especially if you’re new to edibles.

CBG Gel Capsules

CBG gel capsules are all about convenience and consistency. You pop one in like a daily vitamin, and you’re good to go. 

They take a bit of time to work, similar to edibles, around 30 minutes to two hours, but they tend to last longer than inhaling CBG, usually between four and eight hours. Capsules are perfect if you like to keep things simple and want a predictable dose each time. 

They’re also great if you’re not a fan of the taste of tinctures or the texture of gummies. Remember that they’re not for those needing instant effects since your body needs time to absorb them.

Taking a CBG Tincture

CBG tinctures are super flexible and easy to use. You just drop some under your tongue, and you’re set! This method lets you feel the effects pretty quickly, usually within 15 to 30 minutes, and the effects stick around for a few hours. 

Tinctures are great if you like to adjust your dose to suit your needs. If you're not a fan of taking them straight, you can easily mix them into your morning smoothie or tea. 

The taste can be a little earthy, though, which isn’t for everyone, but they’re a solid option if you’re after something quick and versatile.

CBG Roll-On Topical

CBG roll-on topicals are perfect for targeting specific areas, like after a workout or when you’re on the go. They work fast, usually within 15 to 20 minutes, as the CBG absorbs right into your skin. 

It’s a great pick if you’re looking to add CBG to your routine without ingesting anything, and it’s super easy to toss in your bag and use whenever you need. Just roll it on the area you want, and you’re good to go. Topicals are especially handy for anyone who prefers to keep their wellness routine external.

The Best CBG Product to Try

Seeing as we just discussed numerous ways to consume CBG, let’s take a closer look at some of the best CBG products on the market, starting with some CBG-infused flower. 

The Best CBG Pre-Rolls

If you’re looking for some premium CBG flower, the Dali’s Dream Blend 3.5g Pre-Rolls are a perfect way to get started. They feature Northern Lights Indica, offering a smooth and calming experience. 

Infused with a blend of premium CBG and other cannabinoids, these prerolls are perfect for unwinding. Enjoy the mellow, earthy flavors and soothing effects that promote relaxation, making it an ideal choice for evening use or unwinding after a long day.

The Best CBG Vape

If you’d rather have a smoother experience, the Clarity Blend Live Resin 1ml Vape Cart is the way to go. The Clarity Blend 1ml Vape Cartridge in Kush Mints by Mellow Fellow delivers a refreshing and uplifting experience. 

Infused with a unique blend of CBG and other cannabinoids, this vape offers smooth, minty flavors with subtle herbal notes. Ideal for those seeking mental clarity and focus, it's perfect for daytime use or whenever you need a clear, balanced mindset. 

Keep in mind that this is cart, but there are CBG disposables as well, with the Blue Dream Creativity Blend 2ml Disposable Vape coming to mind. 

This disposable vape is designed to spark your imagination. Infused with a mix of CBG and several other cannabinoids, this vape offers the classic sweet berry and earthy flavors of Blue Dream. Perfect for creative minds, it provides a smooth, uplifting experience that helps you tap into your artistic side.

The Best CBG Edibles

For those who want to consume their CBG orally, these Creativity Blend Live Resin M-Fusion Edibles are the way to go. The Creativity Blend Live Resin M Fusions Edibles in Fruit Punch flavor by Mellow Fellow delivers 500mg of premium cannabinoids, including CBG, to elevate your creative potential. 

These edibles offer a delicious fruit punch taste with a balanced, uplifting effect, perfect for boosting focus and artistic inspiration. Ideal for those seeking a flavorful, convenient way to enhance their creative flow.

The Best CBG Tinctures

For those who would want an easy-to-dose product that lets you know exactly how much CBG you’re taking, The Happy Blend Wellness Tincture is worth looking into. The Elevate Blend CBG Tincture by Mellow Fellow offers 2000mg of high-quality CBG, CBD, CBC, and more. with a refreshing berry flavor. 

This tincture is crafted to provide a balanced, uplifting effect, making it ideal for those looking to support overall wellness and boost their daily routine. Easy to use, it’s perfect for adding to your favorite drinks or taking sublingually for quick results.

The Best CBG Gel Capsules

If you just want a super easy experience, gel capsules are the way to go, in which case these Sleep Blend Gel Capsules are a good choice to consider. The 1500mg Rest Blend is designed to support relaxation and a peaceful mindset. 

Each capsule delivers a precise dose of high-quality CBG, combined with other cannabinoids, making it convenient for daily use. Perfect for those seeking a simple, effective addition to their wellness routine without the fuss of measuring or mixing.

The Best CBG Roll-Ons

For those looking for relief of local pain or inflammation, a roll-on such as the Lavender Relief Blend Roll On Gel could be the best option. 

The Mellow Fellow Relief Blend CBD Roll-On Gel with 5000mg of CBG, CBD, and other cannabinoids, along with soothing lavender offers targeted relief with a convenient roll-on application. 


Ideal for on-the-go use, this gel is designed to help ease tension and provide a calming effect with its potent blend of cannabinoids and aromatic lavender, making it perfect for those needing quick, localized relief.

Final Thoughts on the Benefits of CBG

CBG is becoming well-regarded as a cannabinoid with great potential, often called the "mother of cannabinoids" for its foundational role in the cannabis plant. Unlike THC, CBG is non-psychoactive, offering a versatile option for those looking to explore cannabinoids without the high. 

Its unique interaction with the endocannabinoid system may contribute to a range of potential benefits, from reducing inflammation to supporting brain health and mood balance. 

Incorporating CBG into your daily routine is straightforward, with various methods such as smoking, vaping, edibles, capsules, tinctures, and topicals available to suit different preferences and needs. As CBG continues to gain recognition for its therapeutic potential, it stands out as a promising natural option for enhancing overall well-being.

Shop Mellow Fellow today for all of the best cannabinoids! 

Frequently Asked Questions

Is CBG Safe to Use Daily?

CBG is generally considered safe for daily use, especially when sourced from reputable brands that provide third-party lab testing. Always start with a lower dose and adjust as needed to find what works best for you.

How Long Do the Effects of CBG Last?

The duration of CBG’s effects depends on the consumption method. Inhaled forms like smoking or vaping usually last 1-4 hours, while edibles and capsules can provide effects for up to 8 hours or more.

Can CBG Help with Relaxation Without Causing Drowsiness?

Yes, CBG is known for its potential calming effects without the drowsiness often associated with 

other cannabinoids. It can help with relaxation and focus, making it suitable for daytime use.


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