Can CBD Blend Tinctures Enhance Your High? 3 Things You Need to Know

Published on Oct 07, 2025 • Reviewed & Updated on Oct 07, 2025

Want to take your cannabis high to the next level? You're not alone. More and more experienced users and wellness enthusiasts are experimenting with methods to enhance their experience. One trick that's flying under the radar? Blending CBD blend tinctures with other cannabinoid products like vapes, prerolls, and even edibles.

This is not just stoner science, though. It all boils down to something called the entourage effect. It's the hypothesis that cannabinoids and terpenes are more powerful together than they are alone. Think of it like a band: THC, CBD, CBG, terpenes, and friends all contribute their own instruments to the party, but when they jam in sync, the music (i.e., your high) is richer, smoother, and stronger.

In this article, we’ll break down how tinctures can enhance the effects of your favorite cannabis products, what science says about it, and how you can use them strategically to create the exact vibe you’re looking for.

1. It’s All About The Entourage Effect

The entourage effect is the reason that tinctures and other cannabinoid products combine so well. What is the entourage effect? It is the complementary effect of cannabinoids, terpenes, and flavonoids when they interact in the body.

Studies have backed up this theory. A double blind study conducted by researchers at John Hopkins University and the University of Colorado found that  “limonene, a commonly occurring terpene in cannabis, when combined with THC can significantly reduce anxiety that can be exacerbated by THC alone.”

So when you combine products- a sublingual tincture, a vape hit, maybe even a preroll- you're essentially layering cannabinoids and terpenes to multiply their combined effects. That can produce a smoother, less jarring high.

Here are some quick examples:

  • CBD + THC → THC is the cannabinoid that produces the classic "high," but too much of it can make some people jittery or anxious. CBD (cannabidiol) won't get you high, but when combined with THC, it can tame the harsh effects of THC, providing a cleaner, more balanced, and productive high.

 

  • CBG + THCv → CBG (cannabigerol) and THCv (tetrahydrocannabivarin) are lesser-known cannabinoids. Both are known for their energizing and clarity inducing properties. Combined with THC, they'll also counteract the heavy, sedating effects of some strains and keep you more alert and motivated.

 

  • CBN + Linalool → CBN (cannabinol) is a mildly sedating cannabinoid, and linalool is a terpene in lavender. Combined, they create a deeply relaxing, sleep-inducing effect, ideal for unwinding at the end of the day.

When you begin stacking these together, tinctures become more than just drops under the tongue, they become the control panel for personalizing your high.

 

2. How CBD Tinctures Can Actually Enhance Your High

Pairing a CBD blend tincture with your favorite vape or pre-roll can potentially change the way you feel. Tinctures deliver cannabinoids sublingually, which means they enter your bloodstream slightly slower than inhaled products.

This slow release extends the effects of THC and smooths out the intensity, making your high last longer and be more even.

  • Balance the buzz: CBD can help soften THC's more intense psychoactive effects, dampening anxiety or jitteriness and bringing out euphoria.

 

  • Layered effects: Terpenes like myrcene, limonene, and linalool in tinctures interact with cannabinoids to produce relaxation, focus, or stimulation depending on the blend.

 

  • Prolong the high:  Instead of an instant rush from vaping or smoking, the tincture offers a second wave of effects, your session richer and more rewarding.

In short, adding a CBD blend tincture to your routine may actually reshape and enhance the high you get from other cannabinoid products.


3. Pick The Right Tincture For Your High

Before you start layering products, it's worth learning what kind of experience each tincture can provide. Each blend is specifically designed with a unique combination of cannabinoids and terpenes, so each one is capable of influencing your high in a different way.

By knowing what each of these does, you can choose the tincture that will complement your THC vape, pre-roll, or edible best, and create a session that's tailored to your mood, energy, or relaxation needs.

Let’s break down how each tincture can play into your cannabis lineup:

Wellness Tincture - Elevate: The Happy Blend - Mint - 2000mg - Mellow Fellow

The Happy Blend (2000mg)

  • What’s inside: Full Spectrum CBD, CBG, CBC, CBDv + Myrcene

  • What it does: Mood-lifting cannabinoids paired with myrcene (a terpene linked to relaxation and anti-anxiety effects).

  • Pair it with: A daytime pre-roll or hybrid vape to bring some balance to your buzz while still keeping the good vibes rolling. Also available in berry flavor. 

The Relief Blend CBD Tincture - 10,000mg - Berry - Mellow Fellow

The Relief Blend (10,000mg)

  • What’s inside: CBD + H4CBD

  • What it does: This is a heavy hitter. H4CBD, a hydrogenated form of CBD, binds more strongly to CB1 receptors than traditional CBD—suggesting it could pack a more noticeable punch.

  • Pair it with: Post-gym or after a long day, alongside a smooth indica vape or an edible. The Relief Blend extends the relaxation without overwhelming the senses. Available in mint as well.

Wellness Tincture - Momentum: The Energy Blend - Mint - 1500mg - Mellow Fellow

The Energy Blend (1500mg)

  • What’s inside: CBD, CBG, CBC, THCv + Limonene

  • What it does: CBG and THCv are known for their uplifting, focus-driven effects, while limonene adds a natural mood boost.

  • Pair it with: A sativa-leaning vape or citrusy pre-roll for daytime productivity or creative sessions. Grab it in mint or berry.

Wellness Tincture - Rest: The Sleepy Blend - Mint - 1500mg - Mellow Fellow

The Rest Blend (1500mg)

  • What’s inside: Full Spectrum CBD, CBN, CBG + Linalool

  • What it does: CBN and linalool are both associated with sedation and sleep support. Add in CBD’s calming baseline, and you’ve got a nighttime powerhouse.

  • Pair it with: A calming edible or a lavender-forward strain in a pre-roll to fully embrace the wind-down.

Timing & Pairing Tips For Maximum Effects 

Now that we’ve looked into the entourage effect and which blend to pick to match your vibe, here are some more tips to maximize your experience.

  1. Stagger Your Timing: Take a tincture sublingually, then vape about 10–15 minutes later. The vape gives you the instant lift, while the tincture eases in to extend the ride.

  2. Balance THC With CBD: If a pre-roll has you feeling too spacey, a dropper of a CBD-heavy tincture like the Happy Blend can mellow things out.

  3. Microdose for Control: Instead of going heavy on one product, combine smaller amounts of each to create a layered, controllable effect.

Mellow Fellow CBD Tinctures

Final Thoughts

Pairing tinctures with vapes, pre-rolls, or edibles isn’t just about getting “more lit”, though it could certainly have that effect. It’s also about smarter cannabis consumption. Tinctures can help you to control, balance, and extend your high in ways that single products alone can’t.

Whether you’re chasing a happy, social vibe, deep body relief, daytime focus, or a restful night’s sleep, there’s a Mellow Fellow blend designed to work with whatever you’re smoking or vaping.

So, next time you light up, don’t sleep on the tinctures. A few drops might be the key to unlocking your best high yet.


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Can CBD Blend Tinctures Enhance Your High? 3 Things You Need to Know - Mellow Fellow
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