The 10 Best Euphoric Strains

Feb 27, 2025

Some Mellow Fellow EUPHORIA gummies and a vape device are set against a yellow-colored background

Are you searching for the most euphoric cannabis strains to heighten your mood and bring more joy into your life?

In this guide, we’ll introduce you to some of the best euphoric strains on the market, each with its unique combination of effects, flavors, and aromas.

Whether you prefer energizing sativas, relaxing indicas, or balanced hybrids, there's a euphoric strain here that will suit your needs and preferences.

Keep reading to find out what the ten best euphoric strains are!

Key Takeaways

  • Euphoric cannabis strains produce uplifting effects that can improve mood, increase energy, and enhance creativity.

  • THC is the primary compound responsible for euphoria, but terpenes like limonene and pinene play a key role in enhancing its effects.

  • Sativa-dominant strains like Strawberry Amnesia and Green Crack provide energetic highs, while hybrids and indicas offer a more balanced or relaxing experience.

  • Research shows that THC increases dopamine release, contributing to feelings of happiness and motivation.

  • Live resin vapes and other high-terpene extracts can intensify the euphoric effects by preserving more of the strain’s natural compounds.

  • Choosing the right strain for euphoria depends on THC content, terpene profile, and your personal tolerance level.

Visit Mellow Fellow to find all the most euphoric strains that will surely put a smile on your face!

A woman enjoying a Mellow Fellow vape

 

Best Euphoric Strains

Plenty of strains are known for producing a strong euphoric effect.

Here are the top seven euphoria-inducing strains for you to try:

#1 Strawberry Amnesia Euphoria Blend 2ml Live Resin Disposable Vape - Strawberry Amnesia (Sativa) - Mellow Fellow

Strawberry Amnesia is a sativa-dominant hybrid strain created by crossing the potent Strawberry Cough and Amnesia strains. This strain is known for its unique combination of flavors and effects.

Terpenes and Flavor

The dominant terpenes in Strawberry Amnesia include myrcene, limonene, and caryophyllene.

Myrcene offers earthy and musky notes with a hint of fruity flavors, limonene provides a citrusy aroma known for its uplifting effects, and caryophyllene adds a spicy, peppery profile with anti-inflammatory properties.

The flavor profile is dominated by sweet strawberry with undertones of citrus and earthiness.

Cannabinoid Content and Potency

In terms of cannabinoids, Strawberry Amnesia typically contains around 22-26% THC and less than 1% CBD.

Effects

Strawberry Amnesia produces cerebral and euphoric highs, characteristic of sativa strains. The effects start with a burst of energy and creativity, making Strawberry Amnesia ideal for daytime use. It also promotes a sense of well-being and happiness, potentially helping to alleviate stress and depression.

Recommendations

For those looking to try Strawberry Amnesia, it’s best to use it during the day due to its energizing effects.

#2 Tahoe OG

Tahoe OG is an indica-dominant hybrid from the legendary OG Kush lineage. This strain is renowned for its potent relaxing effects and rich flavor profile.

Terpenes and Flavor

The primary terpenes found in Tahoe OG include myrcene, limonene, and pinene. Myrcene contributes to its earthy and musky aroma, limonene offers a citrusy zest, and pinene provides a refreshing pine scent that enhances its overall bouquet.

The flavor profile is a blend of lemon, pine, and earthy undertones, soothing and invigorating to the palate.

Cannabinoid Content and Potency

In terms of cannabinoids, Tahoe OG usually boasts THC levels of around 20-25%, with minimal CBD content.

Effects

The effects of Tahoe OG are relaxing and calming, ideal for evening use or winding down after a long day. You may experience a heavy body sensation paired with a sense of mental tranquility, making it perfect for alleviating stress, anxiety, and insomnia.

Recommendations

If you’re considering trying Tahoe OG, its strong sedative effects make it best suited for evening or nighttime use. Beginners should start with a lower dose to avoid overwhelming couch-lock and fully enjoy the soothing and tranquilizing benefits this strain offers.

The Tranquility Euphoria Live Resin 4ml Vape Cart Duos offer a balanced and uplifting experience by combining these renowned euphoric strains: Strawberry Amnesia and Tahoe OG.

The convenient and discreet 4ml vape cart duo allows you to enjoy the benefits of both strains without drawing unwanted attention. The compact size makes it easy to take on the go, ensuring that a dose of euphoria is always within reach whenever you need a mood boost.

#3 Green Crack Strain

Euphoria Blend 2ml Live Resin Disposable Vape - Green Crack (Sativa) - Mellow Fellow

If you're looking for a strain that delivers an instant burst of euphoria and energy, look no further than Green Crack.

This sativa-dominant strain is renowned for its uplifting and invigorating effects, making it the perfect choice for those seeking a mood boost and a creative spark. Originally bred by crossing Skunk #1 with an unknown indica, Green Crack has earned a reputation for its powerful cerebral high.

Terpenes and Flavor

The primary terpenes in Green Crack are myrcene, pinene, and caryophyllene. Myrcene provides earthy and musky notes, pinene contributes a fresh pine aroma, and caryophyllene adds a spicy, peppery touch.

Its flavor profile is a delightful mix of citrus, mango, and earthiness, making it both refreshing and enjoyable.

Cannabinoid Content and Potency

Regarding cannabinoids, Green Crack typically contains THC levels ranging from 15-25%, with very low CBD content.

Effects

Green Crack's effects are highly stimulating and euphoric, making it an excellent choice for daytime use. These often include heightened focus, creativity, and an overall sense of well-being. It’s handy for combating fatigue, stress, and depression.

Recommendations

Due to its energizing effects, Green Crack is best used during the day. It's ideal for tackling tasks, engaging in creative projects, or enjoying an active outdoor day.

The Euphoria Blend Green Crack 4ml Live Resin Disposable Vape Vol. 1 takes this iconic strain to the next level by using Live Resin extraction.

This process captures the strain's full spectrum of cannabinoids and terpenes, resulting in a more potent and flavorful experience than traditional distillate vapes.

#4 Truffle Butter

Truffle Butter is an indica-dominant hybrid, a cross between Gelato and Chocolate Kush. This is a cherished strain for its rich and decadent flavor and deeply relaxing effects.

Terpenes and Flavor

The main terpenes in Truffle Butter include myrcene, limonene, and linalool. Myrcene brings an earthy and musky aroma, limonene adds a burst of citrus, and linalool contributes a floral and slightly spicy scent.

The flavor profile is a blend of sweet vanilla, creamy butter, and earthy undertones, offering a truly indulgent experience.

Cannabinoids and Potency

Truffle Butter typically features THC levels between 18-25%, with minimal CBD content.

Effects

The effects of Truffle Butter are predominantly relaxing and soothing, making it perfect for evening use. Truffle Butter produces a soothing body high that eases tension and promotes a state of calm, which is excellent for managing stress, pain, and insomnia.

Recommendations

If you’re considering trying Truffle Butter, it’s best suited for nighttime use due to its strong relaxing effects. This strain is ideal for winding down after a long day or preparing for a restful night's sleep.

#5 Sundae Driver

Euphoria Blend 2ml Disposable Vape - Sundae Driver (Hybrid) - Mellow Fellow

Sundae Driver is a balanced hybrid strain, a cross between Fruity Pebbles OG and Grape Pie. It is celebrated for its sweet, creamy flavor and mellow effects.

Terpenes and Flavor

The dominant terpenes in Sundae Driver include caryophyllene, limonene, and linalool. Caryophyllene brings a peppery, spicy aroma, limonene adds a citrusy brightness, and linalool contributes a floral, lavender-like scent.

The bouquet is reminiscent of a dessert, with notes of sweet cream, chocolate, and fruity undertones, making it a delight for the senses.

Cannabinoids and Potency

Sundae Driver typically features THC levels between 14-21%, with minimal CBD content.

Effects

The effects of Sundae Driver are balanced and calming, providing both mental relaxation and mild physical relief. Expect to experience a gentle euphoria and a sense of well-being, making it a great choice for managing stress, anxiety, and minor pain.

Recommendations

Sundae Driver is a versatile strain suitable for daytime and evening use. Start with a moderate dose to enjoy its balanced effects without feeling too sedated. It's an excellent choice for those seeking relaxation and a mild, enjoyable high without being overwhelmed.

The Euphoria Blend Truffle Butter and Sundae Driver 2ml Cartridge Duo offers a one-of-a-kind euphoric experience that tantalizes your taste buds and elevates your mood. This dynamic combination brings together two highly sought-after strains with distinct flavor profiles and effects.

#6 Chemdawg

Chemdawg is a legendary hybrid strain that has gained a strong following due to its potent effects and distinct flavor profile. The lineage of Chemdawg is somewhat mysterious, but it's widely believed to be a cross between Thai and Nepalese sativa strains.

Terpenes and Flavor

The dominant terpenes in Chemdawg include myrcene, limonene, and caryophyllene.

Myrcene imparts earthy and herbal notes, limonene adds a citrusy zest, and caryophyllene contributes a spicy, peppery kick.

The flavor profile is characterized by an intense mix of diesel, earthiness, and pine, making it robust and memorable.

Cannabinoids and Potency

Chemdawg typically features THC levels ranging from 15-20%, with minimal CBD content.

Effects

The effects of Chemdawg are balanced and powerful, offering a mix of cerebral stimulation and full-body relaxation. It produces a euphoric and creative high that can help alleviate stress, anxiety, and pain, making it suitable for both daytime and evening use.

Recommendations

Chemdawg is versatile enough to be used at any time of day. This strain is ideal for those seeking a potent and memorable high that can boost mental and physical well-being.

If you're searching for a strain that delivers a potent and long-lasting euphoric experience, try our Euphoria Blend Chemdawg 4ml Live Resin Disposable Vape Vol. 2.

This classic strain has earned its reputation as a go-to choice for those seeking an uplifting and cerebral high that will leave you feeling blissful and energized.

The combination of Chemdawg's cerebral effects and the potency of Live Resin ensures an unforgettable experience that will elevate your mood and leave you feeling blissful for hours on end.

#7 Miami I-95 Kush

Rounding out our list is Miami I-95 Kush. It is an indica-dominant hybrid that combines the genetics of Triangle Kush, Legend OG, and Stardawg. This strain is known for its potent effects and complex flavor profile.

Terpenes and Flavor

The main terpenes found in Miami I-95 Kush are myrcene, caryophyllene, and limonene. Myrcene offers an earthy and musky aroma, caryophyllene adds a spicy, peppery note, and limonene provides a touch of citrusy brightness.

The flavor profile includes a blend of diesel, earthiness, and a hint of citrus, making it both robust and invigorating. 

The Live Resin extraction process preserves the strain's natural terpene profile, capturing the essence of I-95 Kush in its purest form. You'll experience a complex array of flavors, including notes of sweet citrus, earthy pine, and a hint of diesel, all contributing to the strain's unique and enjoyable taste.

Cannabinoids and Potency

Miami I-95 Kush typically contains THC levels between 20-27%, with minimal CBD content.

Effects

The effects of Miami I-95 Kush are deeply relaxing and euphoric, making it ideal for evening use.

Expect to experience a strong body high paired with a sense of mental calm and happiness, making it effective for alleviating stress, pain, and insomnia.

Recommendations

If you’re considering trying Miami I-95 Kush, it’s best suited for nighttime use due to its strong sedative effects. This strain is perfect for winding down after a long day and ensuring a restful night's sleep.

You can experience this strain at Mellow Fellow with the Euphoria Miami I-95 Kush Hybrid 1ml Live Resin Disposable Vape.

#8. Pandora’s Box

Euphoria Blend 2ml Vape Cartridge - Pandora's Box (Sativa) - Mellow Fellow

Pandora’s Box is a sativa-dominant hybrid bred by crossing Jack the Ripper and Space Queen. This strain delivers an uplifting and energetic high, making it a favorite for those seeking a mentally stimulating experience.

Terpenes and Flavor

Pandora’s Box features a terpene profile dominated by limonene, myrcene, and caryophyllene. Limonene contributes bright citrus notes while enhancing mood, myrcene provides herbal, earthy undertones with a touch of sweetness, and caryophyllene adds a slight spice and may have soothing properties.

The flavor is a mix of zesty citrus, pine, and a subtle spice, creating a refreshing and slightly tangy taste.

Cannabinoid Content and Potency

Pandora’s Box typically contains THC levels ranging from 13% to 22%, with low CBD content, usually averaging at roughly 19%.

Effects

This strain delivers an energetic and thought-provoking high, making it a great option for daytime use. Users often experience heightened focus, creativity, and a noticeable boost in mood. Many also report feelings of excitement and laughter, making it a solid choice for social settings. 

Recommendations

Due to its potent cerebral effects, Pandora’s Box is best suited for experienced users looking for a stimulating, mood-enhancing strain. It's ideal for those who want to stay active, whether working on creative projects or enjoying outdoor activities. This Pandora’s Box Vape Cart makes for a great way to try this strain in a convenient and user friendly format. 

#9. Berry Pie

Berry Pie is a sativa-dominant strain bred by Cookies x Seed Junkie Genetics. Just as the name suggests, this strain delivers a deliciously sweet aroma reminiscent of freshly baked blueberry waffles. Its energizing and mood-boosting effects make it an excellent choice for those looking to stay focused and uplifted.

Terpenes and Flavor

Berry Pie boasts a rich terpene profile dominated by limonene, myrcene, and caryophyllene. Limonene brings a citrusy zest while promoting an elevated mood, myrcene contributes to the strain’s sweet, fruity aroma with calming properties, and caryophyllene adds a hint of spice, potentially easing stress and tension.

The flavor is a delightful mix of sweet blueberry, creamy vanilla, and a touch of tartness, giving it a dessert-like quality.

Cannabinoid Content and Potency

Berry Pie typically contains THC levels around 22% and low CBG content (1%).

Effects

This strain delivers a strong cerebral high that enhances creativity, focus, and sociability. Many users report feeling a wave of confidence and motivation, making it an ideal choice for daytime use. The euphoric lift is balanced by a light body relaxation, helping to melt away stress without causing sedation. Overconsumption may lead to dry mouth, dizziness, or mild paranoia.

Recommendations

Berry Pie is great for those who enjoy flavorful strains with an uplifting effect. Whether you're tackling creative projects, engaging in social activities, or just looking for a pick-me-up, this strain offers a blissful and invigorating experience that keeps you moving. If this sounds like an experience worth trying, the Euphoria Blend Berry Pie Spinner Vape is the perfect place to start. 

#10. Green Goblin

Green Goblin is a sativa-dominant hybrid that stems from a cross between Northern Lights and Skunk #1. This strain delivers an energetic and cerebral high, often paired with a light body relaxation that lingers even after the mind clears.

Terpenes and Flavor

Green Goblin’s pungent aroma carries musky and skunky notes, underscored by a distinct diesel scent. Hints of citrus and pine come through on the exhale, adding a refreshing sharpness to its bold profile. The presence of limonene and caryophyllene contributes to both its uplifting effects and its slightly spicy, herbal undertones.

Cannabinoid Content and Potency

Green Goblin typically features THC levels around 14% with low CBG content (1%), making it slightly less potent than some high-THC sativas but still offering a noticeable and stimulating high. There are some specimens that can reach 24% THC, but these are few and far in between. 

Effects

This strain is best known for its ability to promote focus, creativity, and an upbeat mood. Users often experience a rush of mental energy that makes it great for daytime use, especially for those needing a boost in motivation and alertness. 

The giggly and social nature of the high also makes it ideal for gatherings or activities that require engagement. Some users report mild dry mouth or paranoia with higher doses.

Recommendations

Green Goblin is perfect for those who enjoy an invigorating and uplifting strain without overwhelming potency. 

Whether you're looking to power through a creative project, stay active, or simply enjoy a lighthearted, happy buzz, this strain delivers a balanced high that keeps you going. If you want to experience this same happy buzz, give the Green Goblin Disposable THCh vape a try! It also happens to be a great way to try a new and increasingly popular cannabinoid: THCh.

What Makes a Strain Euphoric?

When searching for the perfect euphoric strain, it's helpful to understand the key factors contributing to those blissful, uplifting effects. Two primary components play a significant role in determining a strain's euphoric potential: THC content and terpene profile.

A lady closes her eyes while enjoying, relaxing, and dancing


Here’s what makes a strain euphoric:

The Role of THC in Euphoria

THC, or tetrahydrocannabinol, is the main psychoactive compound in cannabis responsible for the "high" associated with consuming marijuana.

Strains with higher THC levels tend to produce more intense euphoric effects, as THC interacts with the brain's endocannabinoid system to stimulate the release of dopamine, a neurotransmitter linked to feelings of pleasure and reward.

An article from Psychology Today suggests that THC stimulates dopamine release, causing euphoria and altered sensory perceptions during a cannabis high. Learn more from Psychology Today.

However, THC content alone doesn't guarantee a euphoric experience. The presence of other cannabinoids, such as CBD, can modulate the effects of THC, potentially tempering its psychoactive impact.

How Terpenes Influence Euphoric Effects

Terpenes, the aromatic compounds found in cannabis and other plants, play a significant role in shaping a strain's effects.

A recent study from Biochemical Pharmacology states that certain terpenes synergize with THC to produce additional effects, potentially enhancing the therapeutic effects of THC, such as mood regulation. In other words, certain terpenes may be able to increase the euphoria-inducing effects of THC. 

Certain terpenes are particularly associated with euphoric, mood-elevating effects:

  • Limonene: This citrusy terpene is known for its uplifting and stress-reducing properties, making it a common feature in strains that deliver a happy, energetic buzz.

  • Pinene: Found in pine needles and herbs like rosemary, pinene is often associated with improved focus and mental clarity, which can contribute to a more cerebral, euphoric high. Studies show that pinene can have positive mood regulating effects

  • Myrcene: While this earthy, musky terpene is often linked to relaxation and sedation, it can also enhance the euphoric effects of THC when present in lower concentrations.

By familiarizing yourself with the terpene profiles of different strains, you can better predict the type of euphoric experience they might offer.

An assortment of Mellow Fellow vapes

How to Choose the Best Cannabis Strains for Euphoria

When selecting a cannabis strain for euphoria, focus on THC content, terpene profile, and strain type. 

Strains with higher THC levels (typically above 20%) tend to produce stronger euphoric effects by stimulating dopamine release. However terpenes like limonene, myrcene, and caryophyllene tend to produce mood elevation and contribute to a more uplifting high.

Sativa-dominant strains are often preferred for cerebral, energetic euphoria, while hybrids can offer a balanced blend of mental uplift and body relaxation. Indica-heavy strains can also induce euphoria but often lean toward deep relaxation and bliss rather than an energizing high.

Ultimately, personal tolerance, body chemistry, and desired effects should guide your choice. If you're sensitive to THC, consider balanced strains with some CBD to smooth out potential overstimulation while still enjoying a dose of euphoria.

Final Thoughts on the Best Strains for Euphoria

Euphoric cannabis strains offer more than just a good high because they can improve mood, boost creativity, and provide relaxation when you need it most. As research continues to confirm the connection between THC, terpenes, and mood regulation, it's clear that certain strains are better suited for delivering uplifting effects. 

Whether you prefer energizing sativas like Green Crack and Pandora’s Box, or relaxing hybrids like Truffle Butter and Miami I-95 Kush, there’s a strain that fits your lifestyle. 

Studies suggest that THC stimulates dopamine release, while terpenes like limonene and pinene amplify its euphoric effects. By choosing a strain based on potency, terpenes, and your personal tolerance, you can enjoy a tailored cannabis experience that boosts happiness and well-being.

Visit our Mellow Fellow shop here for all of the best euphoric strains. 

Frequently Asked Questions

What Is the Best Type of Cannabis Strain for Euphoria?

Sativa-dominant strains tend to produce the strongest euphoric effects, as they provide an energetic, mood-lifting high. However, balanced hybrids and some indicas can also create a deep sense of happiness and relaxation.

Do Terpenes Really Affect How Euphoric a Strain Feels?

Yes, terpenes play a significant role in shaping a strain’s effects. Limonene, pinene, and caryophyllene are known to enhance mood and amplify THC’s euphoric qualities.

Can Low-THC Strains Still Create a Euphoric Feeling?

Strains with lower THC can still produce euphoria, especially if they contain uplifting terpenes. However, higher THC strains generally offer a more pronounced euphoric effect.

How Does Live Resin Extraction Affect Euphoria?

Live resin preserves more terpenes and cannabinoids compared to standard distillates, leading to a more flavorful and potent high that enhances euphoria.

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